Evidence map›Paper›PMID 28252078›Full record

ArticleNature2017

Drug screening: Don't discount all curcumin trial data.

Michal Heger

Abstract readLetterComment
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. ACS omega · 2021
    Article
  11. Curcumin Acetylsalicylate Extends the Lifespan ofMolecules (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Targeted Transdermal Delivery of Curcumin for Breast Cancer Prevention.International journal of environmental research and public health · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Michal HegerUniversity of Amsterdam, the Netherlands.

Funding

Preclinical Pharmacogenomics and Synaptic Biomarkers for Alzheimer's DiseaseR01AT006816 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COLE, GREGORY M, FRAUTSCHY, SALLY ANN · 2011 to 2015
$1.9M
Polyphenolic Interventions for tau Pathogenesis in Alzheimers ModelsI01BX001257 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI FRAUTSCHY, SALLY ANN · 2013 to 2016
–
Curcumin and Yoga Exercise Effects in Veterans at Risk for Alzheimer's DiseaseI01RX000669 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI FRAUTSCHY, SALLY ANN · 2015 to 2015
–
BLRD VA I01 BX001257NCCIH NIH HHS R01 AT006816RRD VA I01 RX000669
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CurcuminDrug Evaluation, PreclinicalCurcumin

Identifiers

PMID28252078
PMCPMC6814206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.