Evidence map›Paper›PMID 28251990›Full record

ReviewNature reviews. Neuroscience2017

Operation and plasticity of hippocampal CA3 circuits: implications for memory encoding.

Nelson Rebola, Mario Carta, Christophe Mulle

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed.

  1. Increased CA3 burst activity inbioRxiv : the preprint server for biology · 2026
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  10. Therapeutic effects ofIBRO neuroscience reports · 2025
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  12. Reactivation of memory-associated neurons induces downstream suppression of competing neuronal populations.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  14. Properties of Hippocampal Mossy Fibre Synapses in VAMP7 KO Mice.The European journal of neuroscience · 2025
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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nelson RebolaUniversity of Bordeaux, Interdisciplinary Institute for Neuroscience, Centre National de la Recherche Scientifique (CNRS), F-33000 Bordeaux, France.
Mario CartaUniversity of Bordeaux, Interdisciplinary Institute for Neuroscience, Centre National de la Recherche Scientifique (CNRS), F-33000 Bordeaux, France.
Christophe MulleUniversity of Bordeaux, Interdisciplinary Institute for Neuroscience, Centre National de la Recherche Scientifique (CNRS), F-33000 Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CA3 region of the hippocampus is important for rapid encoding of memory. Computational theories have proposed specific roles in hippocampal function and memory for the sparse inputs from the dentate gyrus to CA3 and for the extended local recurrent connectivity that gives rise to the CA3 autoassociative network. Recently, we have gained considerable new insight into the operation and plasticity of CA3 circuits, including the identification of novel forms of synaptic plasticity and their underlying mechanisms, and structural plasticity in the GABAergic control of CA3 circuits. In addition, experimental links between synaptic plasticity of CA3 circuits and memory are starting to emerge.

Indexed as

AnimalsCA3 Region, HippocampalDendritesGABAergic NeuronsMemoryModels, NeurologicalNeural PathwaysNeuronal Plasticity

Identifiers

PMID28251990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.