SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017
Systematic review of the health-related quality of life issues facing adolescents and young adults with cancer.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Updating our understanding of health-related quality of life issues in children with cancer: a systematic review of patient-reported outcome measures and qualitative studies.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Pooled it
- A critical evaluation of the content validity of patient-reported outcome measures assessing health-related quality of life in children with cancer: a systematic review.Journal of patient-reported outcomes · 2023Pooled it
- Patient reported outcomes in oncology: changing perspectives-a systematic review.Health and quality of life outcomes · 2022Pooled it
- Self-efficacy in symptom management for adolescents and young adults with cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Trial
- Manifestations of Body Image Distress in AYA Cancer Survivors: A Qualitative Analysis of Participants in an Expressive Writing Intervention.Psycho-oncology · 2026Article
- Relations in young adults with cancer: acknowledging partners and friends as caregivers-a Danish national study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Exercise for survivorship: outcomes associated with a community-based group exercise program for adolescent and young adult cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Unmet cancer rehabilitation needs and access to survivorship services across the cancer continuum.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Article
- Patient-Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study.Pediatric blood & cancer · 2026Article
- Adolescents and young adults with predominantly low grade primary central nervous system tumors: patient reported socioeconomic outcomes and health-related quality of life ten years after diagnosis.Journal of neuro-oncology · 2026Article
- Risk factors for lateral and skip lymph node metastasis in adolescents and young adults with papillary thyroid carcinoma.Gland surgery · 2026Article
- Exploration of the relevance and comprehensibility of the European Organization for the Research and Treatment of Cancer Sexual Health Questionnaire among Danish young adults aged 18-39: a national cross-sectional study.Journal of patient-reported outcomes · 2025Article
- Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults With Cancer: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Development of a Health-Related Quality of Life Tool for Adolescents and Young Adults With Cancer.JAMA network open · 2025Article
- Podcasts as a platform for sharing and disseminating experiences and expertise between young adults with cancer and radiotherapy researchers.Research involvement and engagement · 2025Article
- Facing the cancer-related life threat as adolescent and young adult (AYA) after initial diagnosis: A qualitative interview study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Identifying latent profiles of quality of life and lifestyle behaviors in cancer survivors: The interplay of sedentary behavior, physical activity, and sleep.Journal of cancer survivorship : research and practice · 2025Article
- Designing a Measure of Body Image: Cognitive Interview Findings from an Adolescent and Young Adult Cancer Sample.Journal of adolescent and young adult oncology · 2025Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeFor adolescents and young adults (AYAs), the impact of a cancer diagnosis and subsequent treatment is likely to be distinct from other age groups given the unique and complex psychosocial challenges of this developmental phase. In this review of the literature, we report the health-related quality of life (HRQoL) issues experienced by AYAs diagnosed with cancer and undergoing treatment.
methodsMEDLINE, EMBASE, CINAHL, PsychINFO and the Cochrane Library Databases were searched for publications reporting HRQoL of AYAs. Issues generated from interviews with AYAs or from responses to patient reported outcome measures (PROMs) were extracted.
results166 papers were reviewed in full and comprised 72 papers covering 69 primary studies, 49 measurement development or evaluation papers and 45 reviews. Of the 69 studies reviewed, 11 (16%) used interviews to elicit AYAs' descriptions of HRQoL issues. The majority of the PROMs used in the studies represent adaptations of paediatric or adult measures. HRQoL issues were organised into the following categories: physical, cognitive, restricted activities, relationships with others, fertility, emotions, body image and spirituality/outlook on life.
conclusionThe HRQoL issues presented within this review are likely to be informative to health care professionals and AYAs. The extensive list of issues suggests that the impact of a cancer diagnosis and treatment during adolescence and young adulthood is widespread and reflects the complexities of this developmental phase.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.