ReviewNeuroscience bulletin2017
Non-human Primate Models for Brain Disorders - Towards Genetic Manipulations via Innovative Technology.
Review in Neuroscience bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Integrated spatial transcriptomic and metabolic profiling identifies molecular networks associated with cognitive performance in the porcine prefrontal cortex.Zoological research · 2026Article
- Development and evaluation of an autism pig model.Lab animal · 2024Article
- Current State of Modeling Human Psychiatric Disorders Using Zebrafish.International journal of molecular sciences · 2023Review
- Time to consider animal data governance: perspectives from neuroscience.Frontiers in neuroinformatics · 2023Article
- Social housing status impacts rhesus monkeys' affective responding in classic threat processing tasks.Scientific reports · 2022Article
- Evolutionary conservation and divergence of the human brain transcriptome.Genome biology · 2021Article
- Bridging the species gap in translational research for neurodevelopmental disorders.Neurobiology of learning and memory · 2019Article
- Assessing behavior and cognition in rodents, nonhuman primates, and humans: where are the limits of translation? .Dialogues in clinical neuroscience · 2019Review
- Vocalization development in common marmosets for neurodegenerative translational modeling.Neurological research · 2018Article
- Prepulse Inhibition of Auditory Cortical Responses in the Caudolateral Superior Temporal Gyrus in Macaca mulatta.Neuroscience bulletin · 2018Article
- Unraveling of Central Nervous System Disease Mechanisms Using CRISPR Genome Manipulation.Journal of central nervous system disease · 2018Review
- Advances in nonhuman primate models of autism: Integrating neuroscience and behavior.Experimental neurology · 2018Review
- Recent Research Progress in Autism Spectrum Disorder.Neuroscience bulletin · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modeling brain disorders has always been one of the key tasks in neurobiological studies. A wide range of organisms including worms, fruit flies, zebrafish, and rodents have been used for modeling brain disorders. However, whether complicated neurological and psychiatric symptoms can be faithfully mimicked in animals is still debatable. In this review, we discuss key findings using non-human primates to address the neural mechanisms underlying stress and anxiety behaviors, as well as technical advances for establishing genetically-engineered non-human primate models of autism spectrum disorders and other disorders. Considering the close evolutionary connections and similarity of brain structures between non-human primates and humans, together with the rapid progress in genome-editing technology, non-human primates will be indispensable for pathophysiological studies and exploring potential therapeutic methods for treating brain disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.