ArticleSurgery today2017
A decrease in the prognostic nutritional index is associated with a worse long-term outcome in gastric cancer patients undergoing neoadjuvant chemotherapy.
Article in Surgery today, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Efficacy of Neoadjuvant Single or Dual Anti-HER-2 Therapy Combined with Chemotherapy in Patients with HER-2-Positive Breast Cancer: A Single-Center Retrospective Study.Asian Pacific journal of cancer prevention : APJCP · 2021Trial
- Prognostic Nutritional Index as an Indicator of Postoperative Morbidity in Patients Undergoing Perioperative Chemotherapy and Surgery for Carcinoma Stomach.Indian journal of surgical oncology · 2025Article
- The modified-Gustave Roussy immune score: assessing immune prognosis in advanced gastric cancer patients at baseline.Future oncology (London, England) · 2025Article
- Impact of nutritional status on pathological response and recurrence-free survival in locally advanced oesophagogastric adenocarcinoma treated with perioperative FLOT therapy.ESMO gastrointestinal oncology · 2025Article
- Dynamic variations in peripheral blood indices and their association with efficacy and adverse reactions of pd- 1 inhibitor combined chemotherapy in patients with advanced gastric cancer.BMC gastroenterology · 2025Article
- Baseline and changes in prognostic nutritional index associate with heart failure hospitalization and all-cause death in patients with cardiac pacemaker.BMC cardiovascular disorders · 2025Observational
- Analysis of the safety and efficacy of laparoscopic gastrojejunostomy following neoadjuvant chemotherapy for gastric pyloric obstruction.Frontiers in oncology · 2025Article
- Prognostic value of the combined fibrinogen and prognostic nutritional index score in resectable gastric cancer.Frontiers in oncology · 2025Article
- Can the Pathological Response in Patients with Locally Advanced Gastric Cancer Receiving Neoadjuvant Treatment Be Predicted by the CEA/Albumin and CRP/Albumin Ratios?Journal of clinical medicine · 2024Article
- Article
- Prognostic nutritional index in predicting survival of patients with gastric or gastroesophageal junction adenocarcinoma: A systematic review.World journal of gastrointestinal oncology · 2024Article
- Safety and feasibility of minimally invasive gastrectomy after neoadjuvant immunotherapy for locally advanced gastric cancer: a propensity score-matched analysis in China.Gastroenterology report · 2024Article
- Positive correlation between persistence of medical nutrition therapy and overall survival in patients with head and neck cancer.Pathology oncology research : POR · 2024Article
- CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer.BMC cancer · 2023Article
- Inflammation and nutritional status indicators as prognostic indicators for patients with locally advanced gastrointestinal stromal tumors treated with neoadjuvant imatinib.BMC gastroenterology · 2023Article
- Effects of different radical distal gastrectomy on postoperative inflammatory response and nutritional status in patients with gastric cancer.Frontiers in surgery · 2023Article
- Lymph node ratio is a prospective prognostic indicator for locally advanced gastric cancer patients after neoadjuvant chemotherapy.World journal of surgical oncology · 2022Article
- Significance of Preoperative Prognostic Nutritional Index in the Perioperative Management of Gastric Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Superiority of Laparoscopic Gastrojejunostomy Combined With Multimodality Therapy for Gastric Outlet Obstruction Caused by Advanced Gastric Cancer.Frontiers in oncology · 2022Article
- Changes in prognostic nutritional index during hospitalization and outcomes in patients with acute heart failure.Heart and vessels · 2022Article
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9 authors.
Funding
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Abstract
purposeThe aim of this study was to evaluate the prognostic impact of the prognostic nutritional index (PNI) in gastric cancer patients undergoing neoadjuvant chemotherapy (NAC).
methodsThis study reviewed 54 patients with gastric cancer who underwent NAC and a subsequent R0 gastrectomy. The PNI before starting NAC and before gastrectomy were calculated using the following formula: 10 × serum albumin (g/dl) + 0.005 × total lymphocyte count (per mm
resultsThe mean pre-NAC and preoperative PNI were 48.3 ± 5.1 and 48.2 ± 4.7, respectively (p = 0.934). The PNI decreased after NAC in 31 patients (57.4%). The pre-NAC PNI and preoperative PNI were not significantly associated with the OS rate. The 3-year OS rate in patients with the decreased PNI values was significantly lower than that in the patients whose PNI values were either maintained or increased (41 vs. 76.4%, p = 0.003). A multivariate analysis revealed that a decreased PNI value was an independent predictor of a poor OS (p = 0.006).
conclusionsDecreased PNI values were associated with worse long-term outcomes in gastric cancer patients undergoing NAC.
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