Evidence map›Paper›PMID 28251341›Full record

ArticleEuropean journal of nutrition2018

Coffee, tea, caffeine, and risk of hypertension: The Singapore Chinese Health Study.

Choy-Lye Chei, Julian Kenrick Loh, Avril Soh, Jian-Min Yuan, Woon-Puay Koh

Abstract read
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In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Choy-Lye CheiOffice of Clinical Sciences, Duke-NUS Medical School, Singapore, 169857, Singapore.
Julian Kenrick LohNational Heart Center Singapore, Singapore, 169609, Singapore.
Avril SohSaw Swee Hock School of Public Health, National University of Singapore, Singapore, 117549, Singapore.
Jian-Min YuanDivision of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
Woon-Puay KohOffice of Clinical Sciences, Duke-NUS Medical School, Singapore, 169857, Singapore. woonpuay.koh@duke-nus.edu.sg.
National University Health System · SGDuke-NUS Medical School · SGNational Heart Centre Singapore · SGUPMC Hillman Cancer Center · US

Funding

Prospective studies of cancer etiology and prevention in Shanghai and SingaporeR01CA144034 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2010 to 2014
$7.0M
Cancer epidemiology cohorts in Shanghai and Singapore UM1CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2014 to 2018
$4.3M
National Cancer Institute NCI R01 CA144034National Cancer Institute UMI CA182876National Medical Research Council NMRC/CSA/0055/2013National Medical Research Council UMI CA182876NCI NIH HHS R01 CA144034NCI NIH HHS UM1 CA182876
6 · The paper itself

Abstract

purposeThe relationship between coffee and tea, and risk of hypertension remains controversial in Western populations. We investigated these associations in an Asian population.

methodsThe Singapore Chinese Health Study is a population-based prospective cohort that recruited 63,257 Chinese aged 45-74 years and residing in Singapore from 1993 to 1998. Information on consumption of coffee, tea, and other lifestyle factors was collected at baseline, and self-reported physician-diagnosed hypertension was assessed during two follow-up interviews (1999-2004, 2006-2010).

resultsWe identified 13,658 cases of incident hypertension after average 9.5 years. Compared to those who drank one cup of coffee/day, the hazard ratios (HR) and 95% confidence intervals (CI) were 0.87 (0.83-0.91) for <weekly drinkers and 0.93 (0.86-1.00) for ≥3 cups/day drinkers. Compared to <weekly drinkers, daily drinkers of black or green tea had slight increase in risk, but these risk estimates were attenuated and became non-significant after adjustment for caffeine. After adjusting for coffee, there was a stepwise dose-response relationship between caffeine intake and hypertension risk; compared to the lowest intake (<50 mg/day), those in the highest intake (≥300 mg/day) had a 16% increase in risk; HR 1.16, 95% CI 1.04-1.31 (p trend = 0.02).

conclusionsDrinking coffee <1 cup/week or ≥3 cups/day had lower risk than drinking one cup/day. Caffeine may account for increased risk in daily tea drinkers and in those who drank one cup of coffee/day. The inverse U-shaped association with coffee suggests that at higher doses, other ingredients in coffee may offset the effect of caffeine and confer benefit on blood pressure.

Indexed as

CoffeeTeaAgedCaffeineFemaleHumansHypertensionMaleMiddle AgedProspective StudiesRisk FactorsSingaporeCaffeineCoffeeTeaCaffeineCoffeeHypertensionProspective studyTea

Identifiers

PMID28251341
OpenAlexW2593131479

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.