Evidence map›Paper›PMID 28251286›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017

Thoracolumbar kyphosis is associated with compressive vertebral fracture in postmenopausal women.

Y Wei, W Tian, G L Zhang, Y W Lv, G Y Cui

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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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  5. Osteoporotic vertebral fractures localized in the lumbar area significantly impact sagittal alignment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
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  14. Vitamin D Deficiency/Insufficiency Is Associated with Risk of Osteoporotic Thoracolumbar Junction Vertebral Fractures.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  15. Article
  16. Diagnosis of vertebral deformities on chest CT and DXA compared to routine lateral thoracic spine X-ray.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Y WeiDepartment of Spine Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China.
W TianDepartment of Spine Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China. dr_weiyi@163.com.
G L ZhangDepartment of Spine Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China.
Y W LvDepartment of Spine Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China.
G Y CuiDepartment of Spine Surgery, Beijing Jishuitan Hospital, Beijing, 100035, China.
Peking University · CNBeijing Jishuitan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of this retrospective cross-sectional study was to examine the relationship between vertebral compression fracture and thoracolumbar Cobb angles. Fracture prevalence was found to be significantly higher for patients with moderate [odds ratio (OR) = 4.78 (2.88-7.95)] or severe kyphosis [OR = 10.7 (5.11-22.40)] than for patients with mild kyphosis. The relationship between degree of thoracolumbar kyphosis and vertebral compression fracture was analyzed.

introductionThe hypothesis that vertebral compression fracture in women is related to thoracolumbar kyphosis severity was tested, and a clinically important cutoff degree of sagittal thoracolumbar Cobb angle (TLCobb) was determined.

methodsDemographic data, clinical data, and quantitative computed tomography (QCT) findings were compiled for 212 postmenopausal women with thoracolumbar fracture (study group) and 150 postmenopausal women with degenerative lumbar disease (control group). Group proportions and characteristics were compared with chi-squared tests and unpaired t tests, respectively.

resultsIn this retrospective cross-sectional study cohort, 17 patients had T11 fractures, 79 had T12 fractures, 89 had L1 fractures, and 27 had L2 fractures. QCT findings and TLCobb differed between the study and control groups (both p < 0.001). No significant differences were found in body mass index (BMI), disk height, or coronal TLCobb. After adjustment for age, BMI, and QCT findings, fracture prevalence was found to be higher in the thoracolumbar kyphosis study group than in the control group [OR = 6.16, 95% confidence interval (CI) 3.88-9.78]. Sagittal TLCobbs of 7.5-15° and >15° were associated with an increased fracture prevalence, with ORs of 4.78 (2.88-7.95) and 10.7 (5.11-22.40), respectively.

conclusionVertebral fracture prevalence in postmenopausal women was found to be associated with thoracolumbar kyphosis. A TLCobb sagittal angle >15° should be considered an indicator for vertebral fracture assessment.

Indexed as

AgedAged, 80 and overCross-Sectional StudiesFemaleFractures, CompressionHumansKyphosisLumbar VertebraeMiddle AgedOsteoporosis, PostmenopausalOsteoporotic FracturesRetrospective StudiesSpinal FracturesThoracic VertebraeTomography, X-Ray ComputedOsteoporosisPostmenopausal womenQuantitative computed tomographyThoracolumbar kyphosisVertebral fracture

Identifiers

PMID28251286
OpenAlexW2594280123

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.