ArticleBMJ innovations2017
Open-source mobile digital platform for clinical trial data collection in low-resource settings.
Article in BMJ innovations, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Use of mobile data collection systems within large-scale epidemiological field trials: findings and lessons-learned from a vector control trial in Iquitos, Peru.BMC public health · 2022Trial
- Life expectancy in clinical practice: assessment, communication, and decision-making.Archives of medical science : AMS · 2026Article
- The Digital Platform and Its Emerging Role in Decentralized Clinical Trials.Journal of medical Internet research · 2024Article
- Using Principles of Digital Development for a Smartphone App to Support Data Collection in Patients With Acute Myocardial Infarction and Physical Activity Intolerance: Case Study.JMIR formative research · 2024Article
- Opportunities and challenges for decentralised clinical trials in sub-Saharan Africa: a qualitative study.BMJ open · 2023Article
- Article
- Introducing field digital data collection systems into seasonal malaria chemoprevention campaigns: opportunities for robust evidence development and national e-health strategies.BMJ global health · 2022Review
- Review
- Comparing Single-Page, Multipage, and Conversational Digital Forms in Health Care: Usability Study.JMIR human factors · 2021Article
- Anomaly Detection Algorithm for Real-World Data and Evidence in Clinical Research: Implementation, Evaluation, and Validation Study.JMIR medical informatics · 2021Article
- A REDCap-based model for online interventional research: Parent sleep education in autism.Journal of clinical and translational science · 2021Article
- A Good Practice-Compliant Clinical Trial Imaging Management System for Multicenter Clinical Trials: Development and Validation Study.JMIR medical informatics · 2019Article
- Mobile health solutions in developing countries: a stakeholder perspective.Health systems (Basingstoke, England) · 2018Review
- Development and Application of Direct Data Capture for Monitoring Medication Compliance in Clinical Trials.Healthcare informatics research · 2017Article
- Using Digital Technologies in Clinical HIV Research: Real-World Applications and Considerations for Future Work.Journal of medical Internet research · 2017Article
- Design and evaluation of a web-based decision support tool for district-level disease surveillance in a low-resource setting.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGovernments, universities and pan-African research networks are building durable infrastructure and capabilities for biomedical research in Africa. This offers the opportunity to adopt from the outset innovative approaches and technologies that would be challenging to retrofit into fully established research infrastructures such as those regularly found in high-income countries. In this context we piloted the use of a novel mobile digital health platform, designed specifically for low-resource environments, to support high-quality data collection in a clinical research study.
objectiveOur primary aim was to assess the feasibility of a using a mobile digital platform for clinical trial data collection in a low-resource setting. Secondarily, we sought to explore the potential benefits of such an approach.
methodsThe investigative site was a research institute in Nairobi, Kenya. We integrated an open-source platform for mobile data collection commonly used in the developing world with an open-source, standard platform for electronic data capture in clinical trials. The integration was developed using common data standards (Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model), maximising the potential to extend the approach to other platforms. The system was deployed in a pharmacokinetic study involving healthy human volunteers.
resultsThe electronic data collection platform successfully supported conduct of the study. Multidisciplinary users reported high levels of satisfaction with the mobile application and highlighted substantial advantages when compared with traditional paper record systems. The new system also demonstrated a potential for expediting data quality review. DISCUSSION AND
conclusionsThis pilot study demonstrated the feasibility of using a mobile digital platform for clinical research data collection in low-resource settings. Sustainable scientific capabilities and infrastructure are essential to attract and support clinical research studies. Since many research structures in Africa are being developed anew, stakeholders should consider implementing innovative technologies and approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.