Evidence map›Paper›PMID 28250417›Full record

ArticleNature structural & molecular biology2017

Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8

InYoung Song, Anna Gil, Rabinarayan Mishra, Dario Ghersi, Liisa K Selin, Lawrence J Stern

Abstract read
In one paragraph

Article in Nature structural & molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 100 citations in OpenAlex.

  1. The ageing immune system and its battle with viruses.The Journal of general virology · 2026
    Review
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

InYoung SongDepartment of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Anna GilDepartment of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Rabinarayan MishraDepartment of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Dario GhersiSchool of Interdisciplinary Informatics, University of Nebraska at Omaha, Omaha, Nebraska, USA.
Liisa K SelinDepartment of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Lawrence J SternDepartment of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0001-9870-8557
University of Massachusetts Chan Medical School · USUniversity of Nebraska at Omaha · US

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Tetramer CoreP01AI049320 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2001 to 2016
$22.3M
T cell and transgenic core U19AI109858 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HUSEBY, ERIC S · 2014 to 2018
$11.9M
Structure and Function of MHC ProteinsR37AI038996 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J. · 2008 to 2017
$4.1M
Structure and Function of Class II MHC ProteinsR01AI038996 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J · 1996 to 2006
$1.6M
Structure and Function of Class II MHC ProteinsR56AI038996 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J · 2007 to 2007
$324k
NCATS NIH HHS UL1 TR001453NIAID NIH HHS P01 AI049320NIAID NIH HHS R01 AI038996NIAID NIH HHS R37 AI038996NIAID NIH HHS R56 AI038996NIAID NIH HHS U19 AI109858
6 · The paper itself

Abstract

A keystone of antiviral immunity is CD8

Indexed as

Amino Acid MotifsAmino Acid SequenceCD8-Positive T-LymphocytesComplementarity Determining RegionsCrystallography, X-RayEpitopes, T-LymphocyteHLA-A2 AntigenHumansImmunodominant EpitopesJurkat CellsMajor Histocompatibility ComplexModels, MolecularPeptidesProtein BindingProtein Structure, SecondaryReceptors, Antigen, T-CellComplementarity Determining RegionsEpitopes, T-LymphocyteHLA-A2 AntigenImmunodominant EpitopesPeptidesReceptors, Antigen, T-Cell

Identifiers

PMID28250417
PMCPMC5383516
OpenAlexW2592170464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.