ArticleHypertension research : official journal of the Japanese Society of Hypertension2017
Relationships between urinary electrolytes excretion and central hemodynamics, and arterial stiffness in hypertensive patients.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Dietary Sodium Intake and Health Indicators: A Systematic Review of Published Literature between January 2015 and December 2019.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Effect of dietary salt restriction on central blood pressure: A systematic review and meta-analysis of the intervention studies.Journal of clinical hypertension (Greenwich, Conn.) · 2020Pooled it
- Current Data on Dietary Sodium, Arterial Structure and Function in Humans: A Systematic Review.Nutrients · 2019Pooled it
- Effects of added salt reduction on central and peripheral blood pressure.Arquivos brasileiros de cardiologiaTrial
- Brachial-ankle pulse wave velocity predicts liver volume in patients with autosomal dominant polycystic kidney disease.PloS one · 2025Article
- The Influence of Dietary Interventions on Arterial Stiffness in Overweight and Obese Subjects.Nutrients · 2023Review
- Association between Perceived Salt Intake and Arterial Stiffness.BioMed research international · 2022Article
- Associations of urinary sodium excretion with central hemodynamics and changes in vascular structure and function at high altitude.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Endogenous Mammalian Cardiotonic Steroids-A New Cardiovascular Risk Factor?-A Mini-Review.Life (Basel, Switzerland) · 2021Review
- Relationship between 24-hour urinary sodium excretion and blood pressure in the adult population in Shandong, China.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Cardiotonic Steroids-A Possible Link Between High-Salt Diet and Organ Damage.International journal of molecular sciences · 2019Review
- Dietary Sodium Restriction Reduces Arterial Stiffness, Vascular TGF-β-Dependent Fibrosis and Marinobufagenin in Young Normotensive Rats.International journal of molecular sciences · 2018Article
- Marinobufagenin is related to elevated central and 24-h systolic blood pressures in young black women: the African-PREDICT Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- The salt-taste threshold in untreated hypertensive patients.Clinical hypertension · 2017Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High sodium intake plays an important role in the onset and exacerbation of hypertension. However, the relationships between urinary electrolytes excretion and central hemodynamics and between urinary electrolyte excretion and arterial stiffness are still the subject of debate. This study sought to clarify the associations of salt intake with central aortic pressure and arterial stiffness indicators. A total of 431 untreated hypertensive individuals were recruited into the study. Twenty-four-hour urinary samples were collected to measure the excretion of urinary electrolytes. Central hemodynamics parameters and brachial-ankle pulse wave velocity (baPWV) were measured. We evaluated the independent relationship between urinary sodium or potassium excretion and the abovementioned indices. The mean 24-h urinary sodium of all subjects was 166.6±70.0 mmol/24 h. With increases in urinary sodium excretion, central blood pressure and baPWV values markedly increased. Multiple regression analysis showed that urinary sodium was independently associated with increases in central systolic blood pressure, central diastolic blood pressure, the augmentation index, and baPWV. Significant correlations were identified between high dietary sodium and central hemodynamics and between high dietary sodium and arterial elasticity. Prospective interventional studies in hypertensive patients may be required to determine the effect of salt intake on central hemodynamics.
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