ArticleHypertension research : official journal of the Japanese Society of Hypertension2017
Reference values of one-point carotid stiffness parameters determined by carotid echo-tracking and brachial pulse pressure in a large population of healthy subjects.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 19 citations in OpenAlex.
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- Monitoring carotid arterial stiffness using non-contrast-enhanced 4D MR angiography.European radiology experimental · 2026Article
- Increasing blood pressure predicts levels of circulating neutrophil extracellular traps in untreated hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Quantitative Thermal Stimulation Using Therapeutic Ultrasound to Improve Cerebral Blood Flow and Reduce Vascular Stiffness.Sensors (Basel, Switzerland) · 2023Article
- Effect of intracranial pressure on photoplethysmographic waveform in different cerebral perfusion territories: A computational study.Frontiers in physiology · 2023Article
- Subclinical cardiovascular disease and polycystic ovary syndrome.Fertility and sterility · 2022Review
- Six-month longitudinal tracking of arterial stiffness and blood pressure in young adults following SARS-CoV-2 infection.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Compliant vascular models 3D printed with the Stratasys J750: a direct characterization of model distensibility using intravascular ultrasound.3D printing in medicine · 2021Article
- Augmentation index predicts mortality in patients with aortic stenosis: an echo-tracking study.The international journal of cardiovascular imaging · 2021Article
- Assessment of Carotid Arterial Stiffness in Community Settings With ARTSENS®.IEEE journal of translational engineering in health and medicine · 2021Article
- Age related structural and functional changes in left ventricular performance in healthy subjects: a 2D echocardiographic study.The international journal of cardiovascular imaging · 2019Article
- Carotid Artery Stiffness and Development of Hypertension in People with Paraplegia and No Overt Cardiovascular Disease: A 7-year Follow-up Study.Journal of cardiovascular echographyArticle
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Authors and funding
7 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Arterial stiffness can predict cardiovascular events, and the aim of this study was to produce age- and sex-specific reference values for echo-tracking carotid stiffness in healthy subjects. A total of 900 subjects (500 males, mean age 45.8±19 years) were enrolled. Common carotid artery stiffness and compliance, using a high-definition echo-tracking ultrasound system, were evaluated. To compare stiffness parameters across the different age groups, individual scores were transformed into T-scores, indicating how many standard deviation (s.d.) units an individual's score was above or below the mean that was observed in the group including same-sex individuals aged 36 to 44 years. Carotid stiffness was similar among genders, except compliance, which was lower in women (P<0.0001). These characteristics were also maintained when the studied population was divided into seven age groups. Stiffness parameters increased significantly with age, but the opposite occurred for compliance. The T-score was found to increase significantly across all age groups, with a steeper increase in stiffness around the age of 60 years in women. For each T-score s.d., the corresponding carotid absolute values for arterial stiffness and compliance were obtained. In a multivariate model, carotid stiffness parameters were constantly and independently associated with age, mean arterial pressure, pulse pressure, heart rate and body mass index. Our study provides a normogram of carotid arterial stiffness and compliance indices obtained with the echo-tracking method in a large population of healthy subjects stratified by gender and age that can be used in clinical practice.
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