Evidence map›Paper›PMID 28250120›Full record

ArticleJournal of virology2017

A Strategy for Cultivation of Retargeted Oncolytic Herpes Simplex Viruses in Non-cancer Cells.

Valerio Leoni, Valentina Gatta, Costanza Casiraghi, Alfredo Nicosia, Biljana Petrovic, Gabriella Campadelli-Fiume

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Valerio LeoniDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Valentina GattaDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Costanza CasiraghiDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Alfredo NicosiaNouscom SRL, Rome, Italy.
Biljana PetrovicDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Gabriella Campadelli-FiumeDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy gabriella.campadelli@unibo.it.
University of Bologna · ITNouscom (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oncolytic herpes simplex virus (HSV) that has been approved for clinical practice and those HSVs in clinical trials are attenuated viruses, often with the neurovirulence gene γ

Indexed as

AnimalsCell LineChlorocebus aethiopsErb-b2 Receptor Tyrosine KinasesGenetic EngineeringHerpesvirus 1, HumanHumansOncolytic VirotherapyOncolytic VirusesSimplexvirusVero CellsViral TropismVirus CultivationERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesHER2HSVoncolytic virusesretargetingVero

Identifiers

PMID28250120
PMCPMC5411604
OpenAlexW2593942048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.