Evidence map›Paper›PMID 28250115›Full record

ReviewJournal of virology2017

Viral Epitranscriptomics.

Edward M Kennedy, David G Courtney, Kevin Tsai, Bryan R Cullen

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. YTHDF1 and YTHDC1 mJournal of virology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Transcriptional expression of mFrontiers in cell and developmental biology · 2022
    Article
  15. HIV reprograms host mNature communications · 2021
    Article
  16. Review
  17. Article
  18. Article
  19. From A to mViruses · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Edward M KennedyDepartment of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, North Carolina, USA.
David G CourtneyDepartment of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, North Carolina, USA.
Kevin TsaiDepartment of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, North Carolina, USA.
Bryan R CullenDepartment of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, North Carolina, USA bryan.cullen@duke.edu.
Duke University · USDuke University Hospital · US

Funding

Viral Oncology Training GrantT32CA009111 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH A. · 1985 to 2023
$8.9M
Effect of m6A editing of RNA on influenza A virus replicationR21AI130574 · NIAID · DUKE UNIVERSITY · PI CULLEN, BRYAN R. · 2017 to 2018
$437k
NCI NIH HHS T32 CA009111NIAID NIH HHS R21 AI130574
6 · The paper itself

Abstract

Although it has been known for over 40 years that eukaryotic mRNAs bear internal base modifications, it is only in the last 5 years that the importance of these modifications has begun to come into focus. The most common mRNA modification, the addition of a methyl group to the

Indexed as

AdenosineDNA VirusesHIV-1HumansMethylationMethyltransferasesRNA, MessengerRNA Processing, Post-TranscriptionalRNA, ViralRNA VirusesAdenosineMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, MessengerRNA, ViralHIV-1mRNA functionmRNA stabilityN6-methyladenosinePosttranscriptional gene regulationRNA modification

Identifiers

PMID28250115
PMCPMC5391447
OpenAlexW4232537483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.