Evidence map›Paper›PMID 28250014›Full record

ArticleG3 (Bethesda, Md.)2017

The Pivotal Role of Protein Phosphorylation in the Control of Yeast Central Metabolism.

Panayotis Vlastaridis, Athanasios Papakyriakou, Anargyros Chaliotis, Efstratios Stratikos, Stephen G Oliver, Grigorios D Amoutzias

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Qualitative Proteomic Profiling ofFoods (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Panayotis VlastaridisBioinformatics Laboratory, Department of Biochemistry & Biotechnology, University of Thessaly, Biopolis, Larisa 41500, Greece.
Athanasios PapakyriakouBioinformatics Laboratory, Department of Biochemistry & Biotechnology, University of Thessaly, Biopolis, Larisa 41500, Greece.
Anargyros ChaliotisBioinformatics Laboratory, Department of Biochemistry & Biotechnology, University of Thessaly, Biopolis, Larisa 41500, Greece.
Efstratios StratikosNational Centre for Scientific Research Demokritos, Agia Paraskevi 15341, Greece.
Stephen G OliverCambridge Systems Biology Centre, University of Cambridge, CB2 1GA, UK sgo24@cam.ac.uk amoutzias@bio.uth.gr.ORCID 0000-0003-3410-6439
Grigorios D AmoutziasBioinformatics Laboratory, Department of Biochemistry & Biotechnology, University of Thessaly, Biopolis, Larisa 41500, Greece sgo24@cam.ac.uk amoutzias@bio.uth.gr.ORCID 0000-0001-5961-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein phosphorylation is the most frequent eukaryotic post-translational modification and can act as either a molecular switch or rheostat for protein functions. The deliberate manipulation of protein phosphorylation has great potential for regulating specific protein functions with surgical precision, rather than the gross effects gained by the over/underexpression or complete deletion of a protein-encoding gene. In order to assess the impact of phosphorylation on central metabolism, and thus its potential for biotechnological and medical exploitation, a compendium of highly confident protein phosphorylation sites (p-sites) for the model organism

Indexed as

BiotechnologyConserved SequenceMolecular Dynamics SimulationPhenotypePhosphoproteinsPhosphorylationProteomeSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsPhosphoproteinsProteomeSaccharomyces cerevisiae Proteinscomparative phosphoproteomicsmetabolismphosphorylationyeast

Identifiers

PMID28250014
PMCPMC5386872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.