Evidence map›Paper›PMID 28249939›Full record

ArticleThe Journal of biological chemistry2017

Regulation of DENND3, the exchange factor for the small GTPase Rab12 through an intramolecular interaction.

Jie Xu, Peter S McPherson

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Genomic Characterization of Prostatic Basal Cell Carcinoma.The American journal of pathology · 2023
    Article
  3. Article
  4. Article
  5. A new actin-binding domain glues autophagy together.The Journal of biological chemistry · 2018
    Article
  6. Article
  7. Article
  8. Into the linker's DENN: A tyrosine's control of autophagy.The Journal of biological chemistry · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jie XuFrom the Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada jie.xu3@mail.mcgill.ca.
Peter S McPhersonFrom the Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada peter.mcpherson@mcgill.ca.
McGill University · CAMontreal Neurological Institute and Hospital · CA

Funding

CIHR MOP-62684
6 · The paper itself

Abstract

The Rab family of small GTPases functions in multiple aspects of cellular membrane trafficking. Proteins bearing a

Indexed as

AnimalsAutophagyCell MembraneChromatographyFluorescence Resonance Energy TransferGuanine Nucleotide Exchange FactorsGuanosine DiphosphateGuanosine TriphosphateHEK293 CellsHeLa CellsHumansImmunoprecipitationMiceMicroscopy, FluorescenceMutationPhosphorylationDENND3 protein, humanDennd3 protein, mouseGuanine Nucleotide Exchange FactorsGuanosine DiphosphateGuanosine TriphosphateRab12 protein, humanrab GTP-Binding ProteinsTyrosineautophagyDENND3DENN domainguanine nucleotide exchange factor (GEF)intramolecular interactionmembrane traffickingoligomerizationphosphorylationphosphotyrosineRab12

Identifiers

PMID28249939
PMCPMC5409492
OpenAlexW2592537500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.