Evidence map›Paper›PMID 28249638›Full record

SynthesisEpidemiology and infection2017

Comparison of QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for diagnosis of latent tuberculosis in haemodialysis (HD) patients: a meta-analysis of κ estimates.

E Ayubi, A Doosti-Irani, A Sanjari Moghaddam, S Khazaei, K Mansori, S Safiri, M Sani, E Mostafavi

Erratum issuedOpen access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

E AyubiDepartment of Epidemiology,School of Public Health, Shahid Beheshti University of Medical Sciences,Tehran,Iran.
A Doosti-IraniDepartment of Epidemiology,School of Public Health, Hamadan University of Medical sciences,Hamadan,Iran.
A Sanjari MoghaddamSchool of Medicine, Shahid Beheshti University of Medical Sciences,Tehran,Iran.
S KhazaeiDepartment of Epidemiology and Biostatistics,School of Public Health, Tehran University of Medical Sciences,Tehran,Iran.
K MansoriSocial Determinants of Health Research Center, Kurdistan University of Medical Sciences,Sanandaj,Iran.
S SafiriDepartment of Public Health,Managerial Epidemiology Research Center, School of Nursing and Midwifery, Maragheh University of Medical Sciences,Maragheh,Iran.
M SaniSchool of Medicine, Zabol University of Medical Sciences,Zabol,Iran.
E MostafaviResearch Centre for Emerging and Reemerging infectious diseases, Pasteur Institute of Iran,Tehran,Iran.
Tehran University of Medical Sciences · IRHamedan University of Medical Sciences · IRKurdistan University of Medical Sciences · IRPasteur Institute of Iran · IRShahid Beheshti University of Medical Sciences · IRUniversity of Maragheh · IRZabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of latent tuberculosis infection (LTBI) is a concern in haemodialysis (HD) patients. Many studies have compared QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for detecting LTBI and reported the κ statistic of agreement between QFT-GIT and TST in HD patients. The present study aimed to systematically review this literature and conduct meta-analysis of individual studies that estimated the κ between QFT-GIT with TST among HD patients. All relevant published studies that were available as full-text were obtained by searching Medline (1950), Web of Sciences (1945), Scopus (1973) through May 2016. The κ was re-estimated from the individual studies and pooled using random effect meta-analysis. Subgroup analysis and meta-regression were applied to evaluate the effect of Bacillus Calmette-Guérin (BCG) vaccination, TST cut-off points, quality of studies, sample size and age on variation of κ estimate. Eight studies involving 901 HD patients were included in meta-analysis. The pooled κ estimate was 0·28 (I 2 = 18·4%, P = 0·239, 95% confidence intervals 0·22-0·34). The discordance of TST-/QFT-GIT+ was more than TST+/QFT-GIT-. History of BCG vaccination, TST cut-off points and age are related to variation of κ estimates. TST and QFT-GIT are not comparable in detecting LTBI in HD patients. The higher TST-/QFT-GIT+ ratio compared with TST+/QFT-GIT- ratio, may indicate the superiority of QFT-GIT over TST for detection LTBI in HD patients.

Indexed as

HumansLatent TuberculosisRenal DialysisTuberculin TestHaemodialysis patientsinterferon-γ release testsmeta-analysistuberculin skin testκ statistic

Identifiers

PMID28249638
PMCPMC9203340
OpenAlexW2592561101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.