Evidence map›Paper›PMID 28249005›Full record

ArticlePloS one2017

Identifying risk factors associated with smear positivity of pulmonary tuberculosis in Kazakhstan.

Sabrina Hermosilla, Paul You, Angela Aifah, Tleukhan Abildayev, Ainur Akilzhanova, Ulan Kozhamkulov, Talgat Muminov, Meruert Darisheva, Baurzhan Zhussupov, Assel Terlikbayeva and 2 more

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  14. Risk factors for tuberculosis: diabetes, smoking, alcohol use, and the use of other drugs.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sabrina HermosillaColumbia University Mailman School of Public Health, Department of Epidemiology, New York, NY, United States of America.ORCID http://orcid.org/0000-0002-4166-815X
Paul YouColumbia University Mailman School of Public Health, Department of Epidemiology, New York, NY, United States of America.
Angela AifahColumbia University School of Social Work, 1255 Amsterdam Avenue, New York, NY, United States of America.
Tleukhan AbildayevNational Center for Tuberculosis Problems, Almaty, Kazakhstan.
Ainur AkilzhanovaCenter for Life Sciences, Nazarbayev University, 53 Kabanbay Batyr Ave., Astana, Republic of Kazakhstan.
Ulan KozhamkulovCenter for Life Sciences, Nazarbayev University, 53 Kabanbay Batyr Ave., Astana, Republic of Kazakhstan.
Talgat MuminovNational Association for TB Specialists, Almaty, Kazakhstan.
Meruert DarishevaColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Baurzhan ZhussupovColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Assel TerlikbayevaColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Nabila El-BasselColumbia University School of Social Work, 1255 Amsterdam Avenue, New York, NY, United States of America.
Neil SchlugerColumbia University Mailman School of Public Health, Department of Epidemiology, New York, NY, United States of America.

Funding

Global Mental Health Research Fellowship: Interventions That Make a DifferenceT32MH096724 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2012 to 2026
$4.4M
NIMH NIH HHS T32 MH096724
6 · The paper itself

Abstract

backgroundSputum smear-positive tuberculosis (TB) patients have a high risk of transmission and are of great epidemiological and infection control significance. Little is known about the smear-positive populations in high TB burden regions, such as Kazakhstan. The objective of this study is to characterize the smear-positive population in Kazakhstan and identify associated modifiable risk factors.

methodsData on incident TB cases' (identified between April 2012 and March 2014) socio-demographic, risk behavior, and comorbidity characteristics were collected in four regions of Kazakhstan through structured survey and medical record review. We used multivariable logistic regression to determine factors associated with smear positivity.

resultsOf the total sample, 193 (34.3%) of the 562 study participants tested smear-positive. In the final adjusted multivariable logistic regression model, sex (adjusted odds ratio (aOR) = 2.0, 95% CI:1.3-3.1, p < 0.01), incarceration (aOR = 3.6, 95% CI:1.2-11.1, p = 0.03), alcohol dependence (aOR = 2.6, 95% CI:1.2-5.7, p = 0.02), diabetes (aOR = 5.0, 95% CI:2.4-10.7, p < 0.01), and physician access (aOR = 2.7, 95% CI:1.3-5.5p < 0.01) were associated with smear-positivity.

conclusionsIncarceration, alcohol dependence, diabetes, and physician access are associated with smear positivity among incident TB cases in Kazakhstan. To stem the TB epidemic, screening, treatment and prevention policies should address these factors.

Indexed as

AdultAlcoholismCytodiagnosisDiabetes MellitusFemaleHumansKazakhstanMaleMiddle AgedSocioeconomic FactorsSputumTuberculosis, Pulmonary

Identifiers

PMID28249005
PMCPMC5332099

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.