Observational studyMedicine2017
Clinicopathological features and surgical options for synchronous colorectal cancer.
Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- ASO Practice Guidelines Series: Resectable Colorectal Cancer.Annals of surgical oncology · 2026Review
- Nodal stage is the key prognostic factor in synchronous and metachronous multiple primary colorectal adenocarcinoma after curative-intent resection: a retrospective study.World journal of surgical oncology · 2026Article
- One patient with synchronous multiple primary colon cancers which is easy to miss: a case report.Frontiers in surgery · 2026Article
- Diagnostic Certainty in Characterizing Liver Lesions in Rectal Cancer: Abbreviated Liver MRI versus CT.Annals of surgical oncology · 2025Article
- Laparoscopic surgery for synchronous double colorectal cancer with obstruction, plus small B cell lymphoma: a case report.Journal of surgical case reports · 2025Article
- Case report: A rare case of three synchronous colon tumors with metastasis to the left inguinal lymph node.Frontiers in oncology · 2024Article
- Short- and long-term results of openWorld journal of gastrointestinal surgery · 2023Article
- Oncologic relevance of genetic alterations in sporadic synchronous and solitary colorectal cancer: a retrospective multicenter study.BMC gastroenterology · 2023Article
- Dissimilar survival and clinicopathological characteristics of mucinous adenocarcinoma located in pancreatic head and body/tail.World journal of gastrointestinal surgery · 2023Article
- Surgical outcomes of left hemicolon sparing resection versus extensive resection in treating synchronous colorectal cancer involving the right-sided colon and sigmoid colon or rectum.World journal of surgical oncology · 2023Article
- Potential predictors for CDX2 expression loss and mismatch repair deficiency in colorectal cancer.Pathology oncology research : POR · 2023Article
- Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses.NPJ genomic medicine · 2022Article
- A 10-Year Evaluation of Short-Term Outcomes After Synchronous Colorectal Cancer Surgery: a Dutch Population-Based Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Endoluminal tumor implant of a colorectal cancer in an anal fistula detected by FISH techniques: a case report.Journal of gastrointestinal oncology · 2021Article
- Synchronous Colorectal Cancer: Improving Accuracy of Detection and Analyzing Molecular Heterogeneity-The Main Keys for Optimal Approach.Diagnostics (Basel, Switzerland) · 2021Article
- A Rare Presentation of Carcinoma Post Cricoid with Unusual Synchronous Primary Malignancy in the Sigmoid Colon.Indian journal of surgical oncology · 2020Article
- Two Histologically Different Primary Malignancies: Synchronous Obstructive Descending Colon Adenocarcinoma and Appendicular Carcinoid Tumor.The American journal of case reports · 2020Article
- A Retrospective Study of Risk Factors for Symptomatic Anastomotic Leakage after Laparoscopic Anterior Resection of the Rectal Cancer without a Diverting Stoma.Gastroenterology research and practice · 2020Article
- Adenocarcinoma at the Ileostomy Site After a Proctocolectomy for Ulcerative Colitis and/or Familial Adenomatous Polyposis: An Overview.Ostomy/wound management · 2018Review
- Clinical analysis and prognosis of synchronous and metachronous multiple primary malignant tumors.Medicine · 2017Observational
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
This study was conducted to investigate the clinicopathological features of synchronous cancers and treatment options according to their locations.Records of 8368 patients with colorectal cancer treated at our center between July 2003 and December 2010 were analyzed retrospectively. All synchronous colorectal cancer patients who underwent surgical treatment were included.Synchronous cancers were identified in 217 patients (2.6%). Seventy-nine patients underwent either total colectomy, subtotal colectomy, or total proctocolectomy; 116 underwent 1 regional resection, including local excision; and 22 underwent 2 regional resections. The mean age was 62 years, slightly higher than that for the single-cancer patients. Synchronous cancers were more common in male patients, more frequently located in the left colon, had more microsatellite instability-high status, and showed more advanced stage than single cancer. Extensive resection was mainly performed for synchronous cancers located in both the right and left colon. Two regional resections were performed for cancers in the right colon and rectum. There were no differences in complication rates or the occurrence of metachronous cancer between the 2-region resection and extensive resection groups. Eight years postoperatively, the mean number of daily bowel movements for these 2 groups were 1.9 and 4.3, respectively.We found that synchronous cancer was different from single cancer in terms of age, gender, location, and pathologic features. Synchronous colorectal cancer requires different treatment strategy according to the distribution of lesions. Comparison between the 2 regional resections and extensive resection approaches suggests that 2 regional resections are preferable.
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