Evidence map›Paper›PMID 28248551›Full record

ArticleAmerican journal of respiratory and critical care medicine2017

Association between Cardiorespiratory Fitness and Lung Health from Young Adulthood to Middle Age.

Lillian R Benck, Michael J Cuttica, Laura A Colangelo, Stephen Sidney, Mark T Dransfield, David M Mannino, David R Jacobs, Cora E Lewis, Na Zhu, George R Washko and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. The impact of periodontitis on physical fitness: a systematic review.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026
    Pooled it
  2. Progenitor Resilience and the Early Onset of Chronic Lung Diseases: NHLBI workshop report.American journal of respiratory cell and molecular biology · 2026
    Article
  3. Article
  4. Article
  5. Prediction of maximum oxygen uptake over time in adults: analysis from the FRIEND registry.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2025
    Article
  6. Review
  7. Airway Mucus Plugs in Community-Living Adults: A Study Protocol.medRxiv : the preprint server for health sciences · 2024
    Article
  8. Article
  9. Airway Mucus Plugs in Community-Living Adults: A Study Protocol.Journal of clinical & experimental pathology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Cardiorespiratory fitness as a mediator in the relationship between lung function and blood pressure in adults.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
  15. Review
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Lillian R Benck1 Division of Pulmonary and Critical Care Medicine and.
Michael J Cuttica1 Division of Pulmonary and Critical Care Medicine and.
Laura A Colangelo2 Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Stephen Sidney3 Division of Research, Kaiser Permanente of Northern California, Oakland, California.
Mark T Dransfield4 Division of Pulmonary, Allergy and Critical Care Medicine, and.
David M Mannino5 Department of Preventive Medicine and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
David R Jacobs6 Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota.
Cora E Lewis7 Division of Preventive Medicine, University of Alabama-Birmingham, Birmingham, Alabama.
Na Zhu8 Department of Internal Medicine, St. Barnabas Hospital, Bronx, New York; and.
George R Washko9 Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts.
Kiang Liu2 Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Mercedes R Carnethon2 Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Ravi Kalhan1 Division of Pulmonary and Critical Care Medicine and.ORCID 0000-0003-2443-0876
Northwestern University · USPulmonary and Critical Care Associates · USBrigham and Women's Hospital · USKaiser Permanente · USPulmonary and Allergy Associates · USSt. Barnabas Hospital · USUniversity of Alabama at Birmingham · USUniversity of Kentucky · USUniversity of Minnesota · US

Funding

Transitions from Impaired Respiratory Health to Lung DiseaseR01HL122477 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RAVI KALHAN · 2014 to 2026
$17.3M
20 YEAR CHANGES IN FITNESS &CARDIOVASCULAR DISEASE RISKR01HL078972 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 2005 to 2008
$6.1M
NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029CNHLBI NIH HHS R01 HL078972NHLBI NIH HHS R01 HL122477
6 · The paper itself

Abstract

rationaleBeyond the risks of smoking, there are limited data on factors associated with change in lung function over time.

objectivesTo determine whether cardiorespiratory fitness was longitudinally associated with preservation of lung health.

methodsProspective data were collected from 3,332 participants in the Coronary Artery Risk Development in Young Adults study aged 18-30 in 1985 who underwent treadmill exercise testing at baseline visit, and 2,735 participants with a second treadmill test 20 years later. The association between cardiorespiratory fitness and covariate adjusted decline in lung function was evaluated. MEASUREMENTS AND MAIN

resultsHigher baseline fitness was associated with less decline in lung function. When adjusted for age, height, race-sex group, peak lung function, and years from peak lung function, each additional minute of treadmill duration was associated with 1.00 ml/yr less decline in FEV

conclusionsGreater cardiopulmonary fitness in young adulthood, less decline in fitness from young adulthood to middle age, and achieving increased fitness from young adulthood to middle age are associated with less decline in lung health over time. Clinical trial registered with www.clinicaltrials.gov (NCT 00005130).

Indexed as

AdolescentAdultAge FactorsCardiorespiratory FitnessExercise TestForced Expiratory VolumeHealth StatusHumansLungMiddle AgedProspective StudiesRespiratory Function TestsSex FactorsVital CapacityYoung Adultexercisephysical fitnessrespiratory epidemiologyrespiratory function tests

Identifiers

PMID28248551
PMCPMC5439017
OpenAlexW2592317026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.