Evidence map›Paper›PMID 28247940›Full record

ArticleJournal of cellular physiology2018

Plasma membrane calcium ATPase 4 (PMCA4) co-ordinates calcium and nitric oxide signaling in regulating murine sperm functional activity.

Kristine E Olli, Kun Li, Deni S Galileo, Patricia A Martin-DeLeon

Abstract read
In one paragraph

Article in Journal of cellular physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. CaAnimal cells and systems · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Sperm Cryopreservation in American Flamingo (Animals : an open access journal from MDPI · 2021
    Article
  14. IP3R Channels in Male Reproduction.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kristine E OlliDepartment of Biological Sciences, University of Delaware, Newark, Delaware.
Kun LiDepartment of Biological Sciences, University of Delaware, Newark, Delaware.
Deni S GalileoDepartment of Biological Sciences, University of Delaware, Newark, Delaware.
Patricia A Martin-DeLeonDepartment of Biological Sciences, University of Delaware, Newark, Delaware.ORCID http://orcid.org/0000-0002-6903-3703
University of Delaware · US

Funding

TOWARDS SOLID-STATE NMR STRUCTURES OF GPCRSP20RR015588 · NCRR · UNIVERSITY OF DELAWARE · PI LENHOFF, ABRAHAM M · 2000 to 2009
$18.2M
Epididymal PMCA4 Expression Functional Impact and Mechanism of Sperm UptakeR03HD073523 · NICHD · UNIVERSITY OF DELAWARE · PI DELEON, PATRICIA ANASTASIA · 2013 to 2014
$153k
NCRR NIH HHS P20 RR015588NICHD NIH HHS R03 HD073523
6 · The paper itself

Abstract

Reduced sperm motility (asthenospermia) and resulting infertility arise from deletion of the Plasma Membrane Ca

Indexed as

Calcium SignalingSperm MotilityAnimalsApoptosisAsthenozoospermiaCalcium-Transporting ATPasesCaveolin 1Cell MembraneFertilityFluorescence Resonance Energy TransferGenetic Predisposition to DiseaseMaleMice, Inbred C57BLMice, Inbred ICRMice, KnockoutMultienzyme ComplexesATP2B4 protein, mouseCalcium-Transporting ATPasesCav1 protein, mouseCaveolin 1Multienzyme ComplexesNitric OxideNitric Oxide Synthase Type INitric Oxide Synthase Type IIINos1 protein, mouseNos3 protein, mousePeroxynitrous Acidasthenospermiacalcium efflux pumpinfertilityoxidative stresssperm damage

Identifiers

PMID28247940
PMCPMC5581300
OpenAlexW2594552496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.