Evidence map›Paper›PMID 28247862›Full record

ArticleCellular and molecular gastroenterology and hepatology2015

Growth Factor Independence-1 (

Xiaoling Qu, Pia Nyeng, Fan Xiao, Jorge Dorantes, Jan Jensen

Open access · bronzeAbstract read
In one paragraph

Article in Cellular and molecular gastroenterology and hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Article
  9. Review
  10. Transcription factor Ptf1a in development, diseases and reprogramming.Cellular and molecular life sciences : CMLS · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Xiaoling QuCleveland Clinic, Department of Stem Cell Biology and Regenerative Medicine, Cleveland, Ohio.
Pia NyengCleveland Clinic, Department of Stem Cell Biology and Regenerative Medicine, Cleveland, Ohio; Danish Stem Cell Center, University of Copenhagen, Copenhagen, Denmark.
Fan XiaoCleveland Clinic, Department of Stem Cell Biology and Regenerative Medicine, Cleveland, Ohio; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Jorge DorantesCleveland Clinic, Department of Stem Cell Biology and Regenerative Medicine, Cleveland, Ohio.
Jan JensenCleveland Clinic, Department of Stem Cell Biology and Regenerative Medicine, Cleveland, Ohio.
Cleveland Clinic · USOttawa Hospital Research InstituteUniversity of Copenhagen · DK

Funding

Defining the Pancreatic Progenitor Mesenchymal NicheR01DK097087 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI JENSEN, JAN, LEACH, STEVEN D · 2013 to 2016
$1.7M
Molecular mechanism of FGF10 signaling in pancreatic developmentR01DK070636 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JENSEN, JAN · 2005 to 2008
$1.1M
NIDDK NIH HHS R01 DK070636NIDDK NIH HHS R01 DK097087
6 · The paper itself

Abstract

BACKGROUND &

aimsThe genetic specification of the compartmentalized pancreatic acinar/centroacinar unit is poorly understood. Growth factor independence-1 (

methods

resultsLoss of

conclusions

Indexed as

BPL, Bauhinia purpurea lectinBrdU, bromodeoxyuridineCACs, centroacinar cellsCentroacinar CellsClaudin 10DIG, digoxigeninEM, electron micrographsGfi1, growth factor independence-1Growth Factor Independence-1 (Gfi1)PBS, phosphate-buffered salineqRT-PCR, quantitative real-time polymerase chain reactionrER, rough endoplasmic reticulumSD, standard deviationTipPC, tip progenitor cellsTrPC, trunk progenitor cellsTUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end labelingWT, wild type

Identifiers

PMID28247862
PMCPMC5301134
OpenAlexW1988259987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.