Evidence map›Paper›PMID 28247317›Full record

SynthesisDrugs & aging2017

Adverse Health Events Related to Self-Medication Practices Among Elderly: A Systematic Review.

Médéa Locquet, Germain Honvo, Véronique Rabenda, Thierry Van Hees, Jean Petermans, Jean-Yves Reginster, Olivier Bruyère

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Drugs & aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Examining the evolution and impact of OTC vending machines in Global Healthcare Systems.Exploratory research in clinical and social pharmacy · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Evaluation of Potential Drug Interactions with AiDKlinikIntegrated pharmacy research & practice · 2022
    Article
  17. Observational
  18. Article
  19. Evaluation of the potential environmental risk from the destination of medicines: an epidemiological and toxicological study.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2021
    Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Médéa LocquetDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. medea.locquet@ulg.ac.be.ORCID 0000-0002-9961-5931
Germain HonvoDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Véronique RabendaDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Thierry Van HeesDepartment of Clinical Pharmacy, CIRM (Center for Interdisciplinary Research on Medicines), University of Liège, Liège, Belgium.
Jean PetermansGeriatric Department, CHU of Liège, Liège, Belgium.
Jean-Yves ReginsterDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Olivier BruyèreDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder adults often resort to self-medication to relieve symptoms of their current illnesses; however, the risks of this practice are multiplied in old age. In particular, this age group is more vulnerable to adverse drug events because of the physiological changes that occur due to senescence.

objectiveThe aim of the study was to obtain an overview of the adverse health events related to self-medication among subjects aged 60 years and over through a systematic review of the literature.

methodsA study of relevant articles was conducted among databases (MEDLINE, PsycINFO, and EBM Reviews-Cochrane Database of Systematic Reviews). Eligibility criteria were established and applied by two investigators to include suitable studies. The results and outcomes of interest were detailed in a descriptive report.

resultsThe electronic search identified 4096 references, and the full texts of 74 were reviewed, of which four were retained in the analysis: three had a cross-sectional design and one prospectively followed elderly subjects. The first study showed a 26.7% prevalence of adverse drug reactions (ADRs) among elders, the second study found a 75% prevalence of side effects, and, finally, a prospective study showed an ADR incidence of 4.5% among self-medicated elders. These studies showed that adverse health events related to self-medication are relatively frequently reported. They also highlighted that analgesics and anti-inflammatory drugs are the most self-medicated products, while vitamins and dietary supplements also appear to be frequently self-administered, but by older individuals.

conclusionsStudies on self-medication in the elderly and its adverse health effects are clearly lacking. There is a need to perform prospective studies on this topic to gain a clear understanding of the extent of this problem and to enhance the awareness of health professionals to better inform seniors.

Indexed as

AdultAgedAnalgesicsAnti-Inflammatory Agents, Non-SteroidalCross-Sectional StudiesDatabases, FactualDrug-Related Side Effects and Adverse ReactionsHumansPrevalenceProspective StudiesSelf MedicationVitaminsAnalgesicsAnti-Inflammatory Agents, Non-SteroidalVitamins

Identifiers

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Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.