Evidence map›Paper›PMID 28247314›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017

Examining health-related quality of life patterns in women with breast cancer.

Laura C Pinheiro, Xianming Tan, Andrew F Olshan, Stephanie B Wheeler, Katherine E Reeder-Hayes, Cleo A Samuel, Bryce B Reeve

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Muscle quality during cancer treatment and associations with health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Trial
  2. Differential patterns of health-related quality of life among low- and high-income cancer survivors in South Korea: a latent class analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Article
  4. Article
  5. Article
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  7. Patterns of Change in Emotional and Functional Well-Being Following Breast Cancer Diagnosis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  8. Overview of Oncology: Drug-Induced Cardiac Toxicity.Medicina (Kaunas, Lithuania) · 2025
    Review
  9. Health-related quality of life profiles of adults with arthritis and/or fibromyalgia: a cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  10. Review
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  13. Patterns of Health-related Quality of Life in Men Who Inject Drugs: A Survey in Southeast Iran.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024
    Article
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  18. Influence of social and behavioral determinants on health-related quality of life among cancer survivors in the USA.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laura C PinheiroDepartment of Health Policy and Management, University of North Carolina, Chapel Hill, USA. lpinheir@live.unc.edu.
Xianming TanDepartment of Biostatistics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
Andrew F OlshanDepartment of Epidemiology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
Stephanie B WheelerDepartment of Health Policy and Management, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
Katherine E Reeder-HayesUniversity of North Carolina Breast Cancer, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
Cleo A SamuelDepartment of Health Policy and Management, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
Bryce B ReeveDepartment of Health Policy and Management, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
UNC Lineberger Comprehensive Cancer CenterUniversity of North Carolina at Chapel Hill · US

Funding

Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHARLES M PEROU · 1992 to 2026
$59.3M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Accountability for Cancer Care through Undoing Racism and Equity (ACCURE)R01CA150980 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CYKERT, SAMUEL NMN, ENG, EUGENIA · 2012 to 2017
$2.9M
NCI NIH HHS P50 CA058223NCI NIH HHS R01 CA150980NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

purposeWe aimed to identify subgroups of women with breast cancer who experience different health-related quality of life (HRQOL) patterns during active treatment and survivorship and determine characteristics associated with subgroup membership.

methodsWe used data from the third phase of the population-based Carolina Breast Cancer Study and included 2142 women diagnosed with breast cancer from 2008 to 2013. HRQOL was measured, on average, 5 and 25 months post diagnosis. Latent profile analysis was used to identify HRQOL latent profiles (LPs) at each time point. Latent transition analysis was used to determine probabilities of women transitioning profiles from 5 to 25 months. Multinomial logit models estimated adjusted odds ratios (aORs) and 95% confidence intervals for associations between patient characteristics and LP membership at each time point.

resultsWe identified four HRQOL LPs at 5 and 25 months. LP1 had the poorest HRQOL and LP4 the best. Membership in the poorest profile at 5 months was associated with younger age aOR 0.95; 0.93-0.96, White race aOR 1.48; 1.25-1.65, being unmarried aOR 1.50; 1.28-1.65 and having public aOR 3.09; 1.96-4.83 or no insurance aOR 6.51; 2.12-20.10. At 25 months, Black race aOR 1.75; 1.18-1.82 was associated with the poorest profile membership. Black race and smoking were predictors of deteriorating to a worse profile from 5 to 25 months.

conclusionsOur results suggest patient-level characteristics including age at diagnosis and race may identify women at risk for experiencing poor HRQOL patterns. If women are identified and offered targeted HRQOL support, we may see improvements in long-term HRQOL and better breast cancer outcomes.

Indexed as

AdultAgedBreast NeoplasmsFemaleHumansMiddle AgedQuality of LifeBreast cancerHealth-related quality of lifeLatent profiles

Identifiers

PMID28247314
PMCPMC5539913
OpenAlexW2591749194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.