ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2017
Junctional neural tube defect in a newborn: report of a fourth case.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Quantitative live imaging reveals PRICKLE1 controls junctional neural tube morphogenesis independent of Planar Cell Polarity.Nature communications · 2026Article
- Junctional Neural Tube Defect : Two Case Report.Journal of Korean Neurosurgical Society · 2025Article
- Severe type of segmental spinal dysgenesis with complete disconnection of the spinal cord and vertebra associated with open neural tube defect.Surgical neurology international · 2023Article
- Junctional Neural Tube Defect (JNTD): A Rare and Relatively New Spinal Dysraphic Malformation.Advances and technical standards in neurosurgery · 2023Article
- Junctional Neurulation : A Junction between Primary and Secondary Neural Tubes.Journal of Korean Neurosurgical Society · 2021Article
- Junctional Neural Tube Defect.Journal of Korean Neurosurgical Society · 2020Article
- Do junctional neural tube defect and segmental spinal dysgenesis have the same pathoembryological background?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Junctional neural tube defect: a supporting case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
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8 authors.
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Abstract
introductionA discontinuous, functionally disconnected spinal cord is an extremely rare finding, with only three known reports in the literature. Titled junctional neural tube defect (JNTD), this newly reported dysraphism is believed to arise from a developmental error occurring during junctional neurulation, a transitory stage of development marked by the end of primary neurulation and the beginning of secondary neurulation. Herein, we report a newborn case of JNTD. CASE REPORT: We report a newborn boy born with anorectal atresia. Physical examination revealed normal movement in the upper and lower extremities. Imaging revealed distal sacral agenesis and a spinal cord that was discontinuous at the thoracolumbar junction. Three vertebral segments inferiorly, at the L2 vertebral level, the distal end of the spinal cord (i.e., conus medullaris) were visualized. No signs of a tethered cord were identified.
conclusionsCharacterized by an error in junctional neurulation in which the primary and secondary NT fail to integrate appropriately, JNTD has been recently classified. We believe the current patient to represent only the fourth reported case of JNTD in the literature.
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