Evidence map›Paper›PMID 28247046›Full record

ReviewResults and problems in cell differentiation

Control of Germline Stem Cell Lineages by Diet and Physiology.

Kaitlin M Laws, Daniela Drummond-Barbosa

Open access · greenAbstract readReview
In one paragraph

Review in Results and problems in cell differentiation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. RNA Sequencing in AdultbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Adipocyte-DerivedBiomolecules · 2025
    Article
  5. Rediscovering theeLife · 2025
    Article
  6. Article
  7. Rediscovering thebioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kaitlin M LawsDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Daniela Drummond-BarbosaDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA. dbarbosa@jhu.edu.
Johns Hopkins University · US

Funding

TRAINING IN AREAS FUNDAMENTAL TO CANCER RESEARCHT32CA009110 · NCI · JOHNS HOPKINS UNIVERSITY · PI MATUNIS, MICHAEL J., WEERARATNA, ASHANI T · 1985 to 2025
$13.1M
Nutrient Sensing in Adipocytes and the Control of Oogenesis in DrosophilaR01GM069875 · NIGMS · VANDERBILT UNIVERSITY · PI DRUMMOND-BARBOSA, DANIELA · 2005 to 2020
$5.2M
NCI NIH HHS T32 CA009110NIGMS NIH HHS R01 GM069875
6 · The paper itself

Abstract

Tight coupling of reproduction to environmental factors and physiological status is key to long-term species survival. In particular, highly conserved pathways modulate germline stem cell lineages according to nutrient availability. This chapter focuses on recent in vivo studies in genetic model organisms that shed light on how diet-dependent signals control the proliferation, maintenance, and survival of adult germline stem cells and their progeny. These signaling pathways can operate intrinsically in the germ line, modulate the niche, or act through intermediate organs to influence stem cells and their differentiating progeny. In addition to illustrating the extent of dietary regulation of reproduction, findings from these studies have implications for fertility during aging or disease states.

Indexed as

DietAnimalsCell DifferentiationCell LineageGerm CellsHumansStress, Physiological

Identifiers

PMID28247046
PMCPMC5505077
OpenAlexW2594728656

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.