Evidence map›Paper›PMID 28247021›Full record

ArticleBrain structure & function2017

Store-operated calcium entry is essential for glial calcium signalling in CNS white matter.

M Papanikolaou, A Lewis, A M Butt

Open access · hybridAbstract read
In one paragraph

Article in Brain structure & function, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Physiology of Oligodendroglia.Advances in neurobiology · 2025
    Review
  6. Article
  7. SOCE as a regulator of neuronal activity.The Journal of physiology · 2024
    Review
  8. Article
  9. Review
  10. CaNeural regeneration research · 2023
    Article
  11. Astrocyte-specific CaBiochemistry and cell biology = Biochimie et biologie cellulaire · 2023
    Review
  12. Review
  13. Article
  14. Characterizing spontaneous CaBiophysical journal · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M PapanikolaouInstitute of Biomedical and Biomolecular Sciences, School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, PO1 2DT, UK.
A LewisInstitute of Biomedical and Biomolecular Sciences, School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, PO1 2DT, UK.
A M ButtInstitute of Biomedical and Biomolecular Sciences, School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, PO1 2DT, UK. arthur.butt@port.ac.uk.
University of Portsmouth · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D012562/1Biotechnology and Biological Sciences Research Council BB/J016888
6 · The paper itself

Abstract

'Calcium signalling' is the ubiquitous response of glial cells to multiple extracellular stimuli. The primary mechanism of glial calcium signalling is by release of calcium from intracellular stores of the endoplasmic reticulum (ER). Replenishment of ER Ca

Indexed as

AnimalsAnimals, NewbornBoron CompoundsCalciumCalcium SignalingGene Expression Regulation, DevelopmentalGlial Fibrillary Acidic ProteinLuminescent ProteinsMiceMice, Inbred C57BLMice, TransgenicMyelin Proteolipid ProteinNeurogliaOptic NerveORAI1 ProteinOrgan Culture Techniques2-aminoethoxydiphenylboraneBoron CompoundsCalciumfluorescent protein 583Glial Fibrillary Acidic ProteinLuminescent ProteinsMyelin Proteolipid ProteinORAI1 ProteinOrai1 protein, mouseRNA, MessengerStim1 protein, mouseStim2 protein, mouseStromal Interaction Molecule 1Stromal Interaction Molecule 2TRPM3 protein, mouseTRPM Cation ChannelsAstrocyteCalcium signallingCRACGliaOligodendrocyteStore-operated calcium channelTRP channelWhite matter

Identifiers

PMID28247021
PMCPMC5585307
OpenAlexW2594265004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.