GuidelineJournal of anesthesia2017
JSA guideline for the management of malignant hyperthermia crisis 2016.
Guideline in Journal of anesthesia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Considerations for diverse RYR1 variants in malignant hyperthermia susceptible patients: a report of two cases.BMC anesthesiology · 2026Article
- Current clinical application of dantrolene sodium.Anesthesia and pain medicine · 2023Review
- Real Evidence and Misconceptions about Malignant Hyperthermia in Children: A Narrative Review.Journal of clinical medicine · 2023Review
- General Anesthesia in Schwartz-Jampel Syndrome: A Case Report.Anesthesiology and pain medicine · 2023Article
- Rapid Dantrolene Administration with Body Temperature Monitoring Is Associated with Decreased Mortality in Japanese Malignant Hyperthermia Events.BioMed research international · 2023Article
- A comprehensive review of malignant hyperthermia: Preventing further fatalities in orthopedic surgery.Journal of orthopaedics · 2018Review
- Sugammadex: Efficacy and Practicality in the Dental Office.Anesthesia progress · 2018Article
- Several new Japanese guidelines issued.Journal of anesthesia · 2017Article
- Anesthetic Management of a Patient With a History of Rhabdomyolysis for Dental Treatment.Anesthesia progress · 2017Article
- A successful anesthetic approach in a patient with Schwartz-Jampel syndrome.Saudi journal of anaesthesiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant hyperthermia (MH) can be fatal if the crisis is not appropriately treated. It is an inherited disease usually triggered by the administration of volatile inhalational anesthetics and/or succinylcholine, a muscle relaxant. In a patient with suspected MH, the mechanism of calcium release from storage in the sarcoplasmic reticulum in the skeletal muscle is abnormally accelerated. Unexplained hypercarbia representing >55 mmHg of end-tidal carbon dioxide, tachycardia, and muscle rigidity (including masseter muscle rigidity) are early signs of the initiation of MH, because the metabolism is accelerated. The body temperature can rise by >0.5 °C/15 min and may reach ≥40 °C. Respiratory and metabolic acidosis, arrhythmia, cola-colored urine, increased levels of serum potassium, and tented T-waves on electrocardiogram are common and can lead to cardiac arrest. MH should be treated by discontinuation of the triggering agents, administration of intravenous dantrolene (initially 1 mg/kg), and reduction of the body temperature. Early diagnosis and sufficient dantrolene with body temperature reduction are essential to relieve the patient's MH crisis. This guideline in Japanese translation has been posted on the website: http://www.anesth.or.jp/guide/pdf/guideline_akuseikounetsu.pdf .
Indexed as
Identifiers
28246924What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.