Evidence map›Paper›PMID 28246889›Full record

ArticleEuropean journal of clinical pharmacology2017

An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list.

Eva Sönnerstam, Maria Sjölander, Maria Gustafsson

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eva SönnerstamDepartment of Pharmacology and Clinical Neuroscience, Division of Clinical Pharmacology, Umeå University, SE-901 87, Umeå, Sweden.
Maria SjölanderDepartment of Pharmacology and Clinical Neuroscience, Division of Clinical Pharmacology, Umeå University, SE-901 87, Umeå, Sweden.
Maria GustafssonDepartment of Pharmacology and Clinical Neuroscience, Division of Clinical Pharmacology, Umeå University, SE-901 87, Umeå, Sweden. maria.gustafsson@umu.se.
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs people get older, their sensitivity to drugs and adverse drug reactions can increase due to pharmacokinetic and pharmacodynamic changes. Older people with dementia are a particularly vulnerable group of people. They are at an increased risk of being prescribed potentially inappropriate medications, which may lead to harmful consequences. The aim of this study was to investigate the prevalence of potentially inappropriate medications among older patients with cognitive impairment.

methodsMedical records for patients aged ≥65 years admitted to two hospitals in Northern Sweden were reviewed. Potentially inappropriate medications were identified using the EU(7)-PIM list as an identification tool.

resultsOf 428 patients included in the study, 40.9% had one or more potentially inappropriate medication prescribed. The most commonly represented potentially inappropriate medication classes were hypnotics and sedatives, cardiovascular drugs and laxatives. The most commonly involved potentially inappropriate medications were zopiclone, digoxin and sodium picosulfate. There was an association seen between having a higher number of medications prescribed and having one or more potentially inappropriate medication.

conclusionPotentially inappropriate medications are prevalent among older people with cognitive impairment living in Northern Sweden. It is important to continuously evaluate the need for potentially inappropriate medications in this patient group, in order to prevent adverse drug reactions, especially among those who have a higher number of medications prescribed.

Indexed as

Potentially Inappropriate Medication ListAgedAged, 80 and overCognitive DysfunctionCross-Sectional StudiesDementiaDrug-Related Side Effects and Adverse ReactionsFemaleHospitalizationHumansInappropriate PrescribingMalePractice Patterns, Physicians'PrevalenceRandomized Controlled Trials as TopicRisk FactorsCognitive impairmentEU(7)-PIM listOlder peoplePotentially inappropriate medications

Identifiers

PMID28246889
PMCPMC5423959
OpenAlexW2594416405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.