Evidence map›Paper›PMID 28246557›Full record

ArticleSchizophrenia research and treatment2017

Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study.

Élisabeth Thibaudeau, Caroline Cellard, Clare Reeder, Til Wykes, Hans Ivers, Michel Maziade, Marie-Audrey Lavoie, William Pothier, Amélie M Achim

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Schizophrenia research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04040829 (Cognitive Remediation and Supported Education in Psychotic Disorders), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04040829 naterminatednot on this mapstarted 2021, after this paper: background citation

Cognitive Remediation and Supported Education in Psychotic Disorders: a Randomized Controlled Trial on the Efficacy and the Best Predictors of Academic Functioning

TypeinterventionalSponsorCentre de Recherche de l'Institut Universitaire en Santé Mentale de QuébecRan2021 to 2023Enrolled9ConditionsPsychotic DisordersArmsCognitive remediation therapy (CR), Supported education (SE), Treatment as usual (TAU)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. International perspective on social cognition in schizophrenia: current stage and the next steps.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Élisabeth ThibaudeauÉcole de Psychologie, Université Laval, Québec, QC, Canada G1V 0A6; Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec, QC, Canada G1J 2G3.ORCID 0000-0001-5603-0856
Caroline CellardÉcole de Psychologie, Université Laval, Québec, QC, Canada G1V 0A6; Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec, QC, Canada G1J 2G3.
Clare ReederInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Til WykesInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Hans IversÉcole de Psychologie, Université Laval, Québec, QC, Canada G1V 0A6.
Michel MaziadeCentre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec, QC, Canada G1J 2G3; Département de Psychiatrie et Neurosciences, Faculté de Médecine, Université Laval, Québec, QC, Canada G1V 0A6.
Marie-Audrey LavoieÉcole de Psychologie, Université Laval, Québec, QC, Canada G1V 0A6; Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec, QC, Canada G1J 2G3.
William PothierÉcole de Psychologie, Université Laval, Québec, QC, Canada G1V 0A6; Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec, QC, Canada G1J 2G3.
Amélie M AchimCentre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Québec, QC, Canada G1J 2G3; Département de Psychiatrie et Neurosciences, Faculté de Médecine, Université Laval, Québec, QC, Canada G1V 0A6.ORCID 0000-0002-7660-0008
Institut Universitaire en Santé Mentale de Québec · CAKing's College London · GBUniversité Laval · CA

Funding

Department of Health RP-PG-0612-20002
6 · The paper itself

Abstract

Schizophrenia is associated with deficits in theory of mind (ToM) (i.e., the ability to infer the mental states of others) and cognition. Associations have often been reported between cognition and ToM, and ToM mediates the relationship between impaired cognition and impaired functioning in schizophrenia. Given that cognitive deficits could act as a limiting factor for ToM, this study investigated whether a cognitive remediation therapy (CRT) that targets nonsocial cognition and metacognition could improve ToM in schizophrenia. Four men with schizophrenia received CRT. Assessments of ToM, cognition, and metacognition were conducted at baseline and posttreatment as well as three months and 1 year later. Two patients reached a significant improvement in ToM immediately after treatment whereas at three months after treatment all four cases reached a significant improvement, which was maintained through 1 year after treatment for all three cases that remained in the study. Improvements in ToM were accompanied by significant improvements in the most severely impaired cognitive functions at baseline or by improvements in metacognition. This study establishes that a CRT program that does not explicitly target social abilities can improve ToM.

Identifiers

PMID28246557
PMCPMC5299218
OpenAlexW2581840651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.