Evidence map›Paper›PMID 28246517›Full record

ArticleKorean journal of radiology

Longitudinal Intrinsic Brain Activity Changes in Cirrhotic Patients before and One Month after Liver Transplantation.

Yue Cheng, Li-Xiang Huang, Li Zhang, Ming Ma, Shuang-Shuang Xie, Qian Ji, Xiao-Dong Zhang, Gao-Yan Zhang, Xue-Ning Zhang, Hong-Yan Ni and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cognitive Function in Liver Transplantation.Current transplantation reports · 2020
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yue ChengDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Li-Xiang HuangDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Li ZhangDepartment of Transplantation Surgery, Tianjin First Central Hospital, Tianjin 300192, China.
Ming MaDepartment of Transplantation Surgery, Tianjin First Central Hospital, Tianjin 300192, China.
Shuang-Shuang XieDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Qian JiDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Xiao-Dong ZhangDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Gao-Yan ZhangSchool of Computer Science and Technology, Tianjin Key Laboratory of Cognitive Computing and Application, Tianjin University, Tianjin 300072, China.
Xue-Ning ZhangDepartment of Radiology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Hong-Yan NiDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Wen ShenDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Tianjin First Center Hospital · CNTianjin Medical University · CNSecond Hospital of Tianjin Medical University · CNTianjin University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the spontaneous brain activity alterations in liver transplantation (LT) recipients using resting-state functional MRI. MATERIALS AND

methodsTwenty cirrhotic patients as transplant candidates and 25 healthy controls (HCs) were included in this study. All patients repeated the MRI study one month after LT. Amplitude of low-frequency fluctuation (ALFF) values were compared between cirrhotic patients (both pre- and post-LT) and HCs as well as between the pre- and post-LT groups. The relationship between ALFF changes and venous blood ammonia levels and neuropsychological tests were investigated using Pearson's correlation analysis.

resultsIn the cirrhotic patients, decreased ALFF in the vision-related regions (left lingual gyrus and calcarine), sensorimotor-related regions (left postcentral gyrus and middle cingulate cortex), and the default-mode network (bilateral precuneus and left inferior parietal lobule) were restored, and the increased ALFF in the temporal and frontal lobe improved in the early period after LT. The ALFF decreases persisted in the right supplementary motor area, inferior parietal lobule, and calcarine. The ALFF changes in the right precuneus were negatively correlated with changes in number connection test-A scores (

conclusionLT improved spontaneous brain activity and the results for associated cognition tests. However, decreased ALFF in some areas persisted, and new-onset abnormal ALFF were possible, indicating that complete cognitive function recovery may need more time.

Indexed as

Liver TransplantationAdultBrainBrain MappingCase-Control StudiesFemaleFrontal LobeHumansLiver CirrhosisMagnetic Resonance ImagingMaleMiddle AgedPsychometricsAmplitude of low-frequency fluctuationBrain activity changeCirrhosisFunctional magnetic resonance imagingHepatic encephalopathyLiver transplantationResting state

Identifiers

PMID28246517
PMCPMC5313525
OpenAlexW2574521370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.