ArticleWorld journal of gastroenterology2017
Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue.
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Resting-state functional MRI activity and connectivity in inflammatory bowel disease: a systematic review.Neuroradiology · 2025Pooled it
- Altered neurovascular coupling and associated neurotransmitter profiles in inflammatory bowel disease with distinct depressive symptoms.Journal of neuroinflammation · 2026Article
- A systematic review of digital and imaging technologies for measuring fatigue in immune mediated inflammatory diseases.NPJ digital medicine · 2025Article
- Deconditioning in quiescent Crohn's disease patients with heightened fatigue perception.Journal of Crohn's & colitis · 2025Article
- Immediate and sustained effects of acupuncture on the default mode network.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
- Vascular Disease Is Associated With Differences in Brain Structure and Lower Cognitive Functioning in Inflammatory Bowel Disease: A Cross-Sectional Study.Inflammatory bowel diseases · 2024Article
- Insights into disability and psycho-social care of patients with inflammatory bowel disease.Frontiers in medicine · 2024Review
- Unraveling the fatigue puzzle: insights into the pathogenesis and management of IBD-related fatigue including the role of the gut-brain axis.Frontiers in medicine · 2024Review
- The relationship between Central Nervous System morphometry changes and key symptoms in Crohn's disease.Brain imaging and behavior · 2023Article
- Dissecting the fatigue experience: A scoping review of fatigue definitions, dimensions, and measures in non-oncologic medical conditions.Brain, behavior, & immunity - health · 2021Article
- The Gut-Brain Axis and Its Role in Controlling Eating Behavior in Intestinal Inflammation.Nutrients · 2021Review
- Fatigue in IBD: epidemiology, pathophysiology and management.Nature reviews. Gastroenterology & hepatology · 2019Review
- The Gut Microbiome Feelings of the Brain: A Perspective for Non-Microbiologists.Microorganisms · 2017Review
Corrections and comments
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Authors and funding
19 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate brain involvement in quiescent Crohn's disease (CD) patients with fatigue using quantitative magnetic resonance imaging (MRI).
methodsMultiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue (defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study groups.
resultsReduced glutamate + glutamine (Glx = Glu + Gln) concentrations (
conclusionThis work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls.
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