Evidence map›Paper›PMID 28246327›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Monoubiquitylation of histone H2B contributes to the bypass of DNA damage during and after DNA replication.

Shih-Hsun Hung, Ronald P Wong, Helle D Ulrich, Cheng-Fu Kao

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Decoding RNF20: an epigenetic modifier and beyond.Frontiers in cell and developmental biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Solo or in Concert: SUMOylation in Pathogenic Fungi.The plant pathology journal · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Histone dynamics during DNA replication stress.Journal of biomedical science · 2021
    Review
  18. RPA-mediated recruitment of Bre1 couples histone H2B ubiquitination to DNA replication and repair.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Shih-Hsun HungInstitute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei 11529, Taiwan.
Ronald P WongInstitute of Molecular Biology, 55128 Mainz, Germany.
Helle D UlrichInstitute of Molecular Biology, 55128 Mainz, Germany ckao@gate.sinica.edu.tw h.ulrich@imb-mainz.de.
Cheng-Fu KaoInstitute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei 11529, Taiwan; ckao@gate.sinica.edu.tw h.ulrich@imb-mainz.de.
Institute of Molecular Biology · DENational Defence Medical Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA lesion bypass is mediated by DNA damage tolerance (DDT) pathways and homologous recombination (HR). The DDT pathways, which involve translesion synthesis and template switching (TS), are activated by the ubiquitylation (ub) of PCNA through components of the

Indexed as

DNA DamageDNA ReplicationAlkylating AgentsChromatinDNA RepairFungal ProteinsHistonesHomologous RecombinationRad51 RecombinaseReplication OriginSignal TransductionUbiquitinUbiquitinationUbiquitin-Protein LigasesAlkylating AgentsChromatinFungal ProteinsHistonesRad51 RecombinaseUbiquitinUbiquitin-Protein LigasesBre1 E3 ubiquitin ligasechromatinDNA damage toleranceH2B ubiquitylationhomologous recombination

Identifiers

PMID28246327
PMCPMC5358361
OpenAlexW2592850216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.