Evidence map›Paper›PMID 28246214›Full record

ArticleDevelopment (Cambridge, England)2017

The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1.

Jun-Yi Zhu, Amy Heidersbach, Irfan S Kathiriya, Bayardo I Garay, Kathryn N Ivey, Deepak Srivastava, Zhe Han, Isabelle N King

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Unraveling the Potential Role of NEDD4-like E3 Ligases in Cancer.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jun-Yi ZhuChildren's National Medical Center, Washington, DC 20010, USA.ORCID 0000-0002-4517-101X
Amy HeidersbachGladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Irfan S KathiriyaGladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Bayardo I GarayGladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Kathryn N IveyGladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Deepak SrivastavaGladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.ORCID 0000-0002-3480-5953
Zhe HanChildren's National Medical Center, Washington, DC 20010, USA zhan@childrensnational.org isabelle.king@gladstone.ucsf.edu.ORCID 0000-0002-5177-7798
Isabelle N KingGladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA zhan@childrensnational.org isabelle.king@gladstone.ucsf.edu.ORCID 0000-0002-3182-7540
Gladstone Institutes · USChildren's National · US

Funding

CARDIOGENESIS--MOLECULAR MECHANISMSR01HL057181 · NHLBI · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI DEEPAK SRIVASTAVA · 1997 to 2026
$14.0M
PREDOCTORAL TRAINING IN BIOMEDICAL SCIENCEST32GM008568 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANSEL, KARL MARK · 1995 to 2019
$6.3M
Modeling Nephrotic Syndrome in Drosophila NephrocytesR01DK098410 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI HAN, ZHE · 2014 to 2022
$3.3M
A novel G protein signaling pathway controlling Drosophila cardiac morphogenesisR01HL090801 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAN, ZHE · 2008 to 2012
$2.0M
Hairy-Related Factors in Cardiac Development and DiseaseK08HL079260 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KING, ISABELLE N · 2005 to 2009
$523k
NHLBI NIH HHS K08 HL079260NHLBI NIH HHS R01 HL057181NHLBI NIH HHS R01 HL090801NIDDK NIH HHS R01 DK098410NIGMS NIH HHS T32 GM008568
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3' Untranslated RegionsActin CytoskeletonActinsAnimalsBody PatterningDrosophila melanogasterDrosophila ProteinsGreen Fluorescent ProteinsHeartMicroRNAsNedd4 Ubiquitin Protein LigasesPhenotypePhosphorylationProtein TransportReceptors, NotchSignal Transduction3' Untranslated RegionsActinsDrosophila ProteinsGreen Fluorescent ProteinsMicroRNAsMIRN1 microRNA, DrosophilaNedd4 protein, DrosophilaNedd4 Ubiquitin Protein LigasesReceptors, NotchUbiquitin-Protein LigasesHeartmiR-1Nedd4Nedd4-2Nedd4L

Identifiers

PMID28246214
PMCPMC5374346
OpenAlexW2594661342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.