Evidence map›Paper›PMID 28246002›Full record

ArticleThe Journal of hospital infection2017

Multi-site and nasal swabbing for carriage of Staphylococcus aureus: what does a single nose swab predict?

B C Young, A A Votintseva, D Foster, H Godwin, R R Miller, L W Anson, A S Walker, T E A Peto, D W Crook, K Knox

Open access · hybridAbstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of hospital infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
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  3. Article
  4. Review
  5. Frontiers in immunology · 2024
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
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  13. High levels of Staphylococcus aureus and MRSA carriage in healthy population of Algiers revealed by additional enrichment and multisite screening.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

B C YoungNuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: bernadette.young@ndm.ox.ac.uk.
A A VotintsevaNuffield Department of Medicine, University of Oxford, Oxford, UK.
D FosterNuffield Department of Medicine, University of Oxford, Oxford, UK.
H GodwinNuffield Department of Medicine, University of Oxford, Oxford, UK.
R R MillerNuffield Department of Medicine, University of Oxford, Oxford, UK.
L W AnsonNuffield Department of Medicine, University of Oxford, Oxford, UK.
A S WalkerNuffield Department of Medicine, University of Oxford, Oxford, UK.
T E A PetoNuffield Department of Medicine, University of Oxford, Oxford, UK.
D W CrookNuffield Department of Medicine, University of Oxford, Oxford, UK.
K KnoxNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarriage of Staphylococcus aureus is a risk for infections. Targeted decolonization reduces postoperative infections but depends on accurate screening.

aimTo compare detection of S. aureus carriage in healthy individuals between anatomical sites and nurse- versus self-swabbing; also to determine whether a single nasal swab predicted carriage over four weeks.

methodsHealthy individuals were recruited via general practices. After consent, nurses performed multi-site swabbing (nose, throat, and axilla). Participants performed nasal swabbing twice-weekly for four weeks. Swabs were returned by mail and cultured for S. aureus. All S. aureus isolates underwent spa typing. Persistent carriage in individuals returning more than three self-swabs was defined as culture of S. aureus from all or all but one self-swabs.

findingsIn all, 102 individuals underwent multi-site swabbing; S. aureus carriage was detected from at least one site from 40 individuals (39%). There was no difference between nose (29/102, 28%) and throat (28/102, 27%) isolation rates: the combination increased total detection rate by 10%. Ninety-nine patients returned any self-swab, and 96 returned more than three. Nasal carriage detection was not significantly different on nurse or self-swab [28/99 (74%) vs 26/99 (72%); χ

conclusionNasal swabs detected the majority of carriage; throat swabs increased detection by 10%. Self-taken nasal swabs were equivalent to nurse-taken swabs and predicted persistent nasal carriage over four weeks.

Indexed as

AdolescentAdultAgedAged, 80 and overCarrier StateFemaleHealthy VolunteersHumansMaleMiddle AgedMolecular TypingSpecimen HandlingStaphylococcal InfectionsStaphylococcus aureusYoung AdultCarriageMulti-site screeningspa typingStaphylococcus aureus

Identifiers

PMID28246002
PMCPMC5490851
OpenAlexW2580546957

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.