Evidence map›Paper›PMID 28245920›Full record

ArticleDevelopmental cell2017

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

Vinay Bulusu, Nicole Prior, Marteinn T Snaebjornsson, Andreas Kuehne, Katharina F Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla

Open access · hybridAbstract read
In one paragraph

Article in Developmental cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 152 citations in OpenAlex.

  1. The Role of Glucose Metabolism inInternational journal of molecular sciences · 2026
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Vinay BulusuDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany; Cell Biology & Biophysics Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Nicole PriorDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Marteinn T SnaebjornssonDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Andreas KuehneInstitute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Katharina F SonnenDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Jana KressDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Frank SteinCell Biology & Biophysics Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Carsten SchultzCell Biology & Biophysics Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Uwe SauerInstitute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Alexander AulehlaDevelopmental Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany. Electronic address: aulehla@embl.de.
European Molecular Biology Laboratory · DEETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How metabolism is rewired during embryonic development is still largely unknown, as it remains a major technical challenge to resolve metabolic activities or metabolite levels with spatiotemporal resolution. Here, we investigated metabolic changes during development of organogenesis-stage mouse embryos, focusing on the presomitic mesoderm (PSM). We measured glycolytic labeling kinetics from

Indexed as

Embryonic DevelopmentGlycolysisSpatio-Temporal AnalysisAnimalsCarbon IsotopesCell DifferentiationComputer SystemsEmbryo, MammalianFluorescence Resonance Energy TransferGene Expression Regulation, DevelopmentalGenes, ReporterGlucoseIn Situ HybridizationKineticsMesodermMetabolic Flux AnalysisCarbon IsotopesGlucosePyruvic Acidaerobic glycolysismammalian embryonic developmentmetabolic gradientsmetabolite sensorpresomitic mesoderm (PSM)real-time imagingsomitesstable isotope tracing

Identifiers

PMID28245920
PMCPMC5337618
OpenAlexW2594683400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.