Evidence map›Paper›PMID 28245860›Full record

ArticleArthritis research & therapy2017

Acupuncture decreased the risk of coronary heart disease in patients with fibromyalgia in Taiwan: a nationwide matched cohort study.

Mei-Yao Wu, Ming-Cheng Huang, Jen-Huai Chiang, Mao-Feng Sun, Yu-Chen Lee, Hung-Rong Yen

Open access · goldAbstract read
In one paragraph

Article in Arthritis research & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mei-Yao WuResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, 2 Yude Road, North District, Taichung, Taiwan.
Ming-Cheng HuangDepartment of Chinese Medicine, China Medical University Hospital, 2 Yude Road, North District, Taichung, Taiwan.
Jen-Huai ChiangHealth Data Management Office, China Medical University Hospital, 2 Yude Road, North District, Taichung, Taiwan.
Mao-Feng SunDepartment of Chinese Medicine, China Medical University Hospital, 2 Yude Road, North District, Taichung, Taiwan.
Yu-Chen LeeDepartment of Chinese Medicine, China Medical University Hospital, 2 Yude Road, North District, Taichung, Taiwan. d5167@mail.cmuh.org.tw.
Hung-Rong YenResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, 2 Yude Road, North District, Taichung, Taiwan. hungrongyen@gmail.com.ORCID 0000-0002-0131-1658
China Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to understand whether acupuncture can decrease the risk of coronary heart disease (CHD) in patients with fibromyalgia.

methodsUsing data from the Taiwanese National Health Insurance Research Database, we performed a propensity score-matched cohort study to analyze patients with fibromyalgia diagnosed between 1 January 2000 and 31 December 2010. Patients who received acupuncture treatment, beginning with their initial date of fibromyalgia diagnosis and extending to 31 December 2010, were regarded as the acupuncture cohort. The no-acupuncture cohort comprised patients who never received acupuncture through 31 December 2010. A Cox regression model was used to adjust for age, sex, comorbidities, and drugs used. The HRs of the acupuncture and no-acupuncture cohorts were compared.

resultsAfter performing a 1:1 propensity score match, 58,899 patients in both cohorts were identified. Baseline characteristics were similar in both cohorts. The cumulative incidence of CHD was significantly lower in the acupuncture cohort (log-rank test, p < 0.001). In the follow-up period, 4389 patients in the acupuncture cohort (17.44 per 1000 person-years) and 8133 patients in the no-acupuncture cohort (38.36 per 1000 person-years) developed CHD (adjusted HR 0.43, 95% CI 0.41-0.45). The beneficial effect of acupuncture on the incidence of CHD was independent of age, sex, comorbidities, and statins used.

conclusionsOur study confirmed that acupuncture reduced the risk of CHD in patients with fibromyalgia in Taiwan. Further clinical and mechanistic studies are warranted.

Indexed as

Acupuncture TherapyAdolescentAdultAgedCohort StudiesComorbidityCoronary Artery DiseaseFemaleFibromyalgiaHumansIncidenceMaleMiddle AgedOutcome Assessment, Health CarePropensity ScoreProportional Hazards ModelsAcupunctureCoronary heart diseaseFibromyalgiaNational Health Insurance Research DatabaseTaiwan

Identifiers

PMID28245860
PMCPMC5331677
OpenAlexW2592137771

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.