Evidence map›Paper›PMID 28245633›Full record

ArticleInternational journal of molecular sciences2017

Bioavailability Comparison of Nine Bioselenocompounds In Vitro and In Vivo.

Kazuaki Takahashi, Noriyuki Suzuki, Yasumitsu Ogra

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kazuaki TakahashiGraduate School of Pharmaceutical Sciences, Chiba University, Chiba Prefecture 263-8522, Japan. afda7638@chiba-u.jp.
Noriyuki SuzukiGraduate School of Pharmaceutical Sciences, Chiba University, Chiba Prefecture 263-8522, Japan. n-suzuki@chiba-u.jp.
Yasumitsu OgraGraduate School of Pharmaceutical Sciences, Chiba University, Chiba Prefecture 263-8522, Japan. ogra@chiba-u.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium (Se) shows biologically ambivalent characteristics in animals. It is an essential element but becomes severely toxic when the amount ingested exceeds the adequate intake level. Its biological, nutritional, and toxicological effects are strongly dependent on its chemical form. In this study, we evaluated the toxicity and bioavailability of nine naturally occurring Se compounds, or the so-called bioselenocompounds, in vivo and in vitro. Selenite and selenocystine showed higher toxicity than the other bioselenocompounds in vitro. In an in vitro membrane permeability study using Caco-2 cells, selenomethionine and

Indexed as

AnimalsBiological AvailabilityCell Line, TumorCell ProliferationCell SurvivalChromatography, LiquidHumansMass SpectrometryMolecular StructureOrganoselenium CompoundsPermeabilityRatsOrganoselenium CompoundsCaco-2inductively coupled plasma mass spectrometry (ICP-MS)plasma glutathione peroxidaseseleniumselenoamino acidselenocyanateselenoprotein Pselenosugarspeciation

Identifiers

PMID28245633
PMCPMC5372522

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.