Evidence map›Paper›PMID 28245628›Full record

Trial reportNutrients2017

Maternal Prebiotic Ingestion Increased the Number of Fecal Bifidobacteria in Pregnant Women but Not in Their Neonates Aged One Month.

Shinji Jinno, Takayuki Toshimitsu, Yoshitaka Nakamura, Takayuki Kubota, Yuka Igoshi, Naoko Ozawa, Shuichi Suzuki, Taiji Nakano, Yoshinori Morita, Takayasu Arima and 4 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Shinji JinnoFood Science Research Laboratories, R&D Division, Meiji Co., Ltd., 540 Naruda, Odawaara Kanagawa 250-0862, Japan. shinji.jinno@meiji.com.
Takayuki ToshimitsuFood Science Research Laboratories, R&D Division, Meiji Co., Ltd., 540 Naruda, Odawaara Kanagawa 250-0862, Japan. takayuki.toshimitsu@meiji.com.
Yoshitaka NakamuraFood Science Research Laboratories, R&D Division, Meiji Co., Ltd., 540 Naruda, Odawaara Kanagawa 250-0862, Japan. yoshitaka.nakamura@meiji.com.
Takayuki KubotaDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. takayuki.kubota@meiji.com.
Yuka IgoshiDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. yuka_nz_kumamoto@hotmail.com.
Naoko OzawaDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. n.ozawa0904@gmail.com.
Shuichi SuzukiDepartment of Pediatrics, National Shimoshizu Hospital, Chiba 284-0003, Japan. seeyou@msj.biglobe.ne.jp.
Taiji NakanoDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. taibokku2000@yahoo.co.jp.
Yoshinori MoritaDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. m0ritan@hotmail.com.
Takayasu ArimaDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. takayasuarima@gmail.com.
Fumiya YamaideDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. fyamaide@chiba-u.jp.
Yoichi KohnoDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. kohnoy@chibah.rofuku.go.jp.
Kentaro MasudaMasuda Maternity Clinic, Chiba 289-2144, Japan. ke-masuda@umin.ac.jp.
Naoki ShimojoDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. shimojo@faculty.chiba-u.jp.
Chiba University · JPShizuoka City Shimizu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fructooligosaccharides (FOS) can selectively stimulate the growth of bifidobacteria. Here, we investigated the effect of maternal FOS ingestion on maternal and neonatal gut bifidobacteria. In a randomized, double-blind, placebo-controlled study, we administered 8 g/day of FOS or sucrose to 84 women from the 26th week of gestation to one month after delivery. The bifidobacteria count was detected using quantitative PCR in maternal (26 and 36 weeks of gestation) and neonatal (one month after delivery) stools. Maternal stool frequency was recorded from 24 to 36 weeks of gestation. The number of fecal

Indexed as

BifidobacteriumPregnancyDNA, BacterialDouble-Blind MethodFecesFemaleHumansInfant, NewbornOligosaccharidesPrebioticsDNA, BacterialfructooligosaccharideOligosaccharidesPrebioticsbifidobacteriaconstipationfecesfructooligosaccharidesinfancyprebioticpregnancystool frequency

Identifiers

PMID28245628
PMCPMC5372859
OpenAlexW2591982222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.