ArticleThe Journal of cell biology1987
Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins.
Article in The Journal of cell biology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 118 citations in OpenAlex.
- A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses inCell reports methods · 2023Article
- γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor.Developmental cell · 2022Article
- Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveals putative downstream effectors of the transcription factor Chinmo.G3 (Bethesda, Md.) · 2021Article
- The FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses.Molecular biology of the cell · 2015Article
- β-Spectrin regulates the hippo signaling pathway and modulates the basal actin network.The Journal of biological chemistry · 2015Article
- Abscission is regulated by the ESCRT-III protein shrub in Drosophila germline stem cells.PLoS genetics · 2015Article
- Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells.PLoS genetics · 2014Article
- Monomeric α-catenin links cadherin to the actin cytoskeleton.Nature cell biology · 2013Article
- Protein phosphatase 1ß limits ring canal constriction during Drosophila germline cyst formation.PloS one · 2013Article
- Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice.Nature · 2012Article
- Spectrin-based skeleton as an actor in cell signaling.Cellular and molecular life sciences : CMLS · 2012Review
- Drosophila ataxin 2-binding protein 1 marks an intermediate step in the molecular differentiation of female germline cysts.Development (Cambridge, England) · 2010Article
- The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster.The Journal of cell biology · 2009Article
- The Cyclin-dependent kinase inhibitor Dacapo promotes genomic stability during premeiotic S phase.Molecular biology of the cell · 2009Article
- The JAK/STAT pathway positively regulates DPP signaling in the Drosophila germline stem cell niche.The Journal of cell biology · 2008Article
- Mago Nashi and Tsunagi/Y14, respectively, regulate Drosophila germline stem cell differentiation and oocyte specification.Developmental biology · 2007Article
- Article
- The fusome mediates intercellular endoplasmic reticulum connectivity in Drosophila ovarian cysts.Molecular biology of the cell · 2004Article
- Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis.The Journal of cell biology · 2000Article
- Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis.Genetics · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Drosophila alpha-spectrin cDNA sequences were isolated from a lambda gt11 expression library. These cDNA clones encode fusion proteins that include portions of the Drosophila alpha-spectrin polypeptide as shown by a number of structural and functional criteria. The fusion proteins elicited antibodies that reacted strongly with Drosophila and vertebrate alpha-spectrins and a comparison of cyanogen bromide peptide maps demonstrated a clear structural correspondence between one fusion protein and purified Drosophila alpha-spectrin. Alpha-spectrin fusion protein also displayed calcium-dependent calmodulin-binding activity in blot overlay experiments and one fusion protein bound specifically to both Drosophila and bovine brain beta-spectrin subunits on protein blots. A region of the Drosophila cDNA cross-hybridized at lowered stringency with an avian alpha-spectrin cDNA. Together these data show that the composition, structure, and binding properties of the spectrin family of proteins have been remarkably well conserved between arthropods and vertebrates. Drosophila cDNA hybridized to an mRNA of greater than or equal to 9 kb on blots of total Drosophila poly A+ RNA; and hybridized in situ to a single site in polytene region 62B, 1-7. This result and Southern blot analysis of genomic DNA indicate that the sequences are likely to be single copy in the Drosophila genome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.