ArticleObesity (Silver Spring, Md.)2017
Influence of genetic variants associated with body mass index on eating behavior in childhood.
Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- The Genetic Basis of Childhood Obesity: A Systematic Review.Nutrients · 2023Pooled it
- Behavioural and genetic correlates of malnutrition.The British journal of nutrition · 2026Article
- Article
- Influence of the Brain-Derived Neurotrophic Factor Gene Polymorphism on Weight Loss Following Intragastric Balloon Intervention: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Behavioural susceptibility theory: the role of appetite in genetic susceptibility to obesity in early life.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants.BioMed research international · 2022Article
- The Role of Eating Behaviours in Genetic Susceptibility to Obesity.Current obesity reports · 2020Review
- Polymorphisms of brain-derived neurotrophic factor genes are associated with anxiety and body mass index in fibromyalgia syndrome patients.BMC research notes · 2020Article
- LMX1B rs10733682 Polymorphism Interacts with Macronutrients, Dietary Patterns on the Risk of Obesity in Han Chinese Girls.Nutrients · 2020Article
- Sleep duration and quality are associated with eating behavior in low-income toddlers.Appetite · 2019Article
- FTO genotype and weight status among preadolescents: Assessing the mediating effects of obesogenic appetitive traits.Appetite · 2017Article
- BMI prediction within a Korean population.PeerJ · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveChildhood eating behaviors are associated with body mass index (BMI). Recent genome-wide association studies have identified many single-nucleotide polymorphisms (SNPs) associated with adult and childhood BMI. This study hypothesized that these SNPs also influence eating behavior.
methodsIn a population-based prospective cohort study among 3,031 children (mean age [standard deviation]: 4.0 [0.1] years), two weighted genetic risk scores, based on 15 childhood and 97 adult BMI SNPs, and ten individual appetite- and/or satiety-related SNPs were tested for association with food fussiness, food responsiveness, enjoyment of food, satiety responsiveness, and slowness in eating.
resultsThe 15 SNP-based childhood BMI genetic risk score was not associated with the eating behavior subscales. The 97 SNP-based adult BMI genetic risk score was nominally associated with satiety responsiveness (β: -0.007 standard deviation, 95% confidence interval [CI] -0.013, 0.000). Of the 10 individual SNPs, rs11030104 in BDNF and rs10733682 in LMX1B were nominally associated with satiety responsiveness (β: -0.057 standard deviation, 95% CI -0.112, -0.002).
conclusionsThese findings do not strongly support the hypothesis that BMI-associated SNPs also influence eating behavior at this age. A potential role for BMI SNPs in satiety responsiveness during childhood was observed; however, no associations with the other eating behavior subscales were found.
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