Evidence map›Paper›PMID 28245075›Full record

ArticleJournal of magnetic resonance imaging : JMRI2017

Lymphedema evaluation using noninvasive 3T MR lymphangiography.

Rachelle Crescenzi, Paula M C Donahue, Katherine G Hartley, Aditi A Desai, Allison O Scott, Vaughn Braxton, Helen Mahany, Sarah K Lants, Manus J Donahue

4 registry-linked trialsAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02611557 nacompletednot on this map

Imaging Noninvasively With Functional-MRI for Onset, Response and Management of Lymphatic Impairment

TypeinterventionalSponsorVanderbilt UniversityRan2015 to 2019Enrolled90ConditionsLymphedema, Breast CancerArmsManual lymphatic drainage therapy
NCT03696433 nacompletednot on this mapstarted 2019, after this paper: background citation

Visualizing Vascular Mechanisms of Salt Sensitivity

TypeinterventionalSponsorVanderbilt University Medical CenterRan2019 to 2022Enrolled19ConditionsObesity, Cardiovascular Risk Factor, Salt, ExcessArmsLow-salt diet, High-salt diet
NCT03760744 nacompletednot on this mapstarted 2019, after this paper: background citation

Imaging Biomarkers of Lymphatic Dysfunction

TypeinterventionalSponsorVanderbilt University Medical CenterRan2019 to 2025Enrolled18ConditionsSecondary LymphedemaArmsCDT with Negative Pressure, CDT alone
NCT05804643 recruitingnot on this mapstarted 2023, after this paper: background citation

Development and Optimization of Novel MRI Techniques on Evaluation of Therapeutic Effects for Lymphedema Secondary to Breast Cancer Treatment: An Integrated Study of Pre-clinical Animal Models and Clinical Follow-up

TypeobservationalSponsorNational Taiwan University HospitalRan2023 to 2026Enrolled210ConditionsLymphedema of Upper LimbArmsDiffusion magnetic resonance imaging
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Vascular changes and their implications in lipedema.Frontiers in cell and developmental biology · 2026
    Review
  3. The choroid plexus water density.Magnetic resonance in medicine · 2026
    Article
  4. The parasagittal dural space of the human brain.Brain : a journal of neurology · 2025
    Review
  5. Review
  6. Magnetic resonance lymphangiography: Establishing normal.Journal of vascular surgery. Venous and lymphatic disorders · 2024
    Article
  7. Article
  8. Article
  9. MRI of Lymphedema.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  10. Choroid plexus perfusion and bulk cerebrospinal fluid flow across the adult lifespan.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Magnetic resonance lymphangiography: with or without contrast?Diagnostic and interventional radiology (Ankara, Turkey) · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rachelle CrescenziRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Paula M C DonahuePhysical Medicine and Rehabilitation, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0003-4656-6539
Katherine G HartleyRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Aditi A DesaiRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Allison O ScottRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Vaughn BraxtonRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Helen MahanyRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Sarah K LantsRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Manus J DonahueRadiology and Radiological Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Vanderbilt University · US

Funding

Quantification of Glymphatic Dysfunction in Patients with Alzheimer's Disease and Related DementiasR01NR015079 · NINR · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DONAHUE, MANUS J · 2014 to 2022
$3.9M
NINR NIH HHS R01 NR015079
6 · The paper itself

Abstract

purposeTo exploit the long 3.0T relaxation times and low flow velocity of lymphatic fluid to develop a noninvasive 3.0T lymphangiography sequence and evaluate its relevance in patients with lymphedema. MATERIALS AND

methodsA 3.0T turbo-spin-echo (TSE) pulse train with long echo time (TE

resultsPatient volunteers demonstrated larger lymphatic cross-sectional areas in the affected (arm = 12.9 ± 6.3 mm

conclusionA 3.0T lymphangiography sequence is proposed, which allows for upper extremity lymph stasis to be detected in ∼10 minutes without exogenous contrast agents. LEVEL OF EVIDENCE: 1 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2017;46:1349-1360.

Indexed as

LymphographyMagnetic Resonance ImagingAdultAgedAged, 80 and overBreast NeoplasmsContrast MediaFemaleHumansImage Processing, Computer-AssistedLymphatic VesselsLymphedemaManual Lymphatic DrainageMiddle AgedSignal Processing, Computer-AssistedSignal-To-Noise RatioContrast Mediabreast cancerlymphangiographylymphedemamanual lymphatic drainageMRIturbo spin echo

Identifiers

PMID28245075
PMCPMC5573666
OpenAlexW2591729483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.