ArticleCongenital heart disease2017
Dysphagia in infants with single ventricle anatomy following stage 1 palliation: Physiologic correlates and response to treatment.
Article in Congenital heart disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Instrumental Swallowing Assessments in the Neonatal and Pediatric Populations: A Systematic Review.Dysphagia · 2022Pooled it
- Enteral Feeding Methods in Patients with Vocal Fold Motion Impairment Following Cardiothoracic Surgery.Pediatric cardiology · 2026Article
- Pulmonary Comorbidities in Children and Young Adults with Fontan Circulation: The Limitations of General Cardiology Clinics Compared with Dedicated Fontan Clinics.Pediatric cardiology · 2026Article
- Prevalence, Clinical Factors and Impact of Dysphagia After Cardiac Surgery for Congenital Heart Disease.Pediatric cardiology · 2026Article
- Time Course and Predictors of Persistent Postoperative Dysphagia in Patients with Congenital Heart Disease Following Cardiac Surgery.Pediatric cardiology · 2026Article
- Using the BaByVFSS Impairment Profile to Characterize the Impact of Thin and Mildly Thick Liquid Consistencies on Validated Physiological Components of Swallowing in Bottle-Fed Children.American journal of speech-language pathology · 2025Article
- Identifying Paediatric Populations with Increased Risk for Oropharyngeal Dysphagia in Acute and Critical Care Settings: A Scoping Review.Dysphagia · 2025Article
- Interstage feeding and caregiver impact on single ventricle patients.Cardiology in the young · 2025Article
- Identification of Molecular Subtypes Associated with PCD in Esophageal Squamous Cell Carcinoma and Analysis of Immune Microenvironment.Current medicinal chemistry · 2025Article
- Non-Pharmacological and Non-Surgical Feeding Interventions for Hospitalized Infants with Pediatric Feeding Disorder: A Scoping Review.Dysphagia · 2023Article
- Prevalence of Feeding and Swallowing Disorders in Congenital Heart Disease: A Scoping Review.Frontiers in pediatrics · 2022Article
- Capturing infant swallow impairment on videofluoroscopy: timing matters.Pediatric radiology · 2020Article
- Aspiration After Congenital Heart Surgery.Pediatric cardiology · 2019Article
- Feeding methods for infants with single ventricle physiology are associated with length of stay during stage 2 surgery hospitalization.Congenital heart disease · 2019Observational
- Feeding Interventions Are Associated With Improved Outcomes in Children With Laryngeal Penetration.Journal of pediatric gastroenterology and nutrition · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDeficits in swallowing physiology are a leading morbidity for infants with functional single ventricles and systemic outflow tract obstruction following stage 1 palliation. Despite the high prevalence of this condition, the underlying deficits that cause this post-operative impairment remain poorly understood.
objectiveIdentify the physiologic correlates of dysphagia in infants with functional single ventricles and systemic outflow tract obstruction following stage 1 palliative surgery.
methodsPostoperative fiberoptic laryngoscopies and videofluoroscopic swallow studies (VFSS) were conducted sequentially on infants with functional single ventricles following stage 1 palliative surgery. Infants were dichotomized as having normal or impaired laryngeal function based on laryngoscopy findings. VFSS were evaluated frame-by-frame using a scale that quantifies performance within 11 components of swallowing physiology. Physiologic attributes within each component were categorized as high functioning or low functioning based on their ability to support milk ingestion without bolus airway entry.
resultsThirty-six infants (25 male) were included in the investigation. Twenty-four underwent the Norwood procedure and twelve underwent the Hybrid procedure. Low function physiologic patterns were observed within multiple swallowing components during the ingestion of thin barium as characterized by ≥4 sucks per swallow (36%), initiation of pharyngeal swallow below the level of the valleculae (83%), and incomplete late laryngeal vestibular closure (56%) at the height of the swallow. Swallowing deficits contributed to aspiration in 50% of infants. Although nectar thick liquids reduced the rate of aspiration (P = .006), aspiration rates remained high (27%). No differences in rates of penetration or aspiration were observed between infants with normal and impaired laryngeal function.
conclusionsDeficits in swallowing physiology contribute to penetration and aspiration following stage 1 palliation among infants with normal and impaired laryngeal function. Although thickened liquids may improve airway protection for select infants, they may inhibit their ability to extract the bolus and meet nutritional needs.
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