Evidence map›Paper›PMID 28244018›Full record

ArticleMedical oncology (Northwood, London, England)2017

Intra-articular benign bone lesions treated with Magnetic Resonance-guided Focused Ultrasound (MRgFUS): imaging follow-up and clinical results.

Francesco Arrigoni, Antonio Barile, Luigi Zugaro, Alessandra Splendiani, Ernesto Di Cesare, Ferdinando Caranci, Anna Maria Ierardi, Chiara Floridi, Alessio Salvatore Angileri, Alfonso Reginelli and 2 more

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In one paragraph

Article in Medical oncology (Northwood, London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Advances in diagnostic and interventional radiology.Acta bio-medica : Atenei Parmensis · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesco ArrigoniDiagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L'Aquila, Italy. arrigoni.francesco@gmail.com.ORCID http://orcid.org/0000-0001-7793-1872
Antonio BarileDiagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L'Aquila, Italy.
Luigi ZugaroDiagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L'Aquila, Italy.
Alessandra SplendianiDiagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L'Aquila, Italy.
Ernesto Di CesareDiagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L'Aquila, Italy.
Ferdinando CaranciDepartment of Medicine and Health Science "V. Tiberio", University of Molise, Campobasso, Italy.
Anna Maria IerardiDepartment of Radiology, Insubria University, Varese, Italy.
Chiara FloridiDepartment of Radiology, Insubria University, Varese, Italy.
Alessio Salvatore AngileriDiagnostic and Interventional Radiology Unit, University of Milan, Milan, Italy.
Alfonso ReginelliDepartment of Internal and Experimental Medicine, Magrassi-Lanzara, Institute of Radiology, Second University of Naples, Naples, Italy.
Luca BruneseDepartment of Medicine and Health Science "V. Tiberio", University of Molise, Campobasso, Italy.
Carlo MasciocchiDiagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L'Aquila, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of this study was to evaluate the employment of MRI-guided Focused Ultrasound (MRgFUS) for treatment of intra-articular benign bone lesions as alternative to surgery, and to monitor the success of the treatment on CT and MRI images. From March 2011 to August 2013, 14 intra-articular benign bone lesions were treated with MRgFUS. All patients were studied by CT and MR imaging. Pain was measured using the visual analogue scale (VAS) before and after treatment (6 and 12 months). All patients in our series demonstrated regression in painful symptomatology during screening. A significant drop in the mean VAS pain score (from 7.8 to 0.6) was observed at 12-month follow-up, and pain medication was no longer needed after treatment. No complications were observed. Three diagnostic imaging signs were found suggesting absence of biological activity and confirming the clinical findings: calcification of the treated lesion, lack of contrast enhancement and disappearance of bone oedema around the lesions.

conclusionthe employment of MRgFUS is safe and effective in the treatment of intra-articular benign bone lesions. The clinical outcome is satisfactory, and the success of the treatment is confirmed by diagnostic imaging.

Indexed as

AdolescentAdultBone NeoplasmsChondromaFemaleFollow-Up StudiesHigh-Intensity Focused Ultrasound AblationHumansMagnetic Resonance ImagingMaleMiddle AgedOsteoma, OsteoidYoung AdultBenign bone lesionsInterventional radiologyIntrarticular bone lesionsMRgFUSOsteoid OsteomaThermoablation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.