Evidence map›Paper›PMID 28243978›Full record

ArticleDrug delivery and translational research2017

Evaluation of in vitro and in vivo anti-urolithiatic activity of silver nanoparticles containing aqueous leaf extract of Tragia involucrata.

Vinodhini Velu, Moonjit Das, Arunai Nambi Raj N, Kamal Dua, Himaja Malipeddi

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Plants (Basel, Switzerland) · 2021
    Review
  6. Article
  7. Article
  8. Ethnopharmacological Use and Biological Activities ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Vinodhini VeluDepartment of Chemistry, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.
Moonjit DasDepartment of Chemistry, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.
Arunai Nambi Raj NDepartment of Physics, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.
Kamal DuaDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, 2007, NSW, Australia.
Himaja MalipeddiDepartment of Chemistry, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632014, India. drmhimaja@gmail.com.
Vellore Institute of Technology University · INUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present investigation is focused on exploring the anti-urolithiatic potential of aqueous leaf extract of Tragia involucrata (TIA) and its silver nanoparticles (AgNPs) and to quantify the total phenol, flavonoid, terpenoid and sterol contents present in TIA. Quantification results suggested TIA to be a rich source of phenol, flavonoid and terpenoid and less of sterol content. The AgNPs were synthesized by a simple green method using aqueous extract of T. involucrata. The formation of AgNPs was confirmed through UV spectroscopy, particle size analysis, zeta potential, X-ray diffraction and transmission electron microscopy. The in vitro struvite growth inhibitory activity of the extract was performed using a single gel diffusion method. Samples incorporated with higher concentration of 2% TIA and AgNPs (200 μg mL

Indexed as

EuphorbiaceaeAnimalsCalcium OxalateGout SuppressantsKidneyMaleMetal NanoparticlesPlant ExtractsPlant LeavesRats, WistarSilverStruviteUrolithiasisCalcium OxalateGout SuppressantsPlant ExtractsSilverStruviteSilver nanoparticlesTragia involucrataUrolithiatic

Identifiers

PMID28243978
OpenAlexW2594481099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.