Evidence map›Paper›PMID 28243938›Full record

ReviewJournal of microbiology (Seoul, Korea)2017

Hemorrhagic fever of bunyavirus etiology: disease models and progress towards new therapies.

Brian B Gowen, Brady T Hickerson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  8. Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections.Frontiers in cellular and infection microbiology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brian B GowenDepartment of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, Utah, 84326, USA. brian.gowen@usu.edu.
Brady T HickersonDepartment of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, Utah, 84326, USA.
Utah State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A growing number of bunyaviruses are known to cause viral hemorrhagic fever (VHF), a severe febrile illness which can progress to hypovolemic shock and multi-organ failure and is characterized by hematologic abnormalities and vascular leak. At present, there are no approved vaccines or antiviral therapies to effectively prevent or treat VHF caused by pathogenic bunyaviruses. Advances in the modeling of bunyaviral infections have facilitated efforts towards the development of novel post-exposure prophylactic and therapeutic countermeasures, several of which may some day be approved for human use. Here, we review recent progress in animal models of severe bunyaviral infections essential to this mission, as well as promising antivirals and biologicals that are at various stages of the development process.

Indexed as

AnimalsAntiviral AgentsBiological FactorsBunyaviridae InfectionsCricetinaeDisease Models, AnimalHantavirus InfectionsHemorrhagic Fever, CrimeanHemorrhagic Fevers, ViralHumansMiceOrthobunyavirusOrthohantavirusPost-Exposure ProphylaxisRatsRift Valley FeverAntiviral AgentsBiological FactorsViral VaccinesantiviralbunyavirusCrimean-Congo hemorrhagic feverhantavirusRift valley feversevere fever with thrombocytopenia syndrome

Identifiers

PMID28243938
OpenAlexW2592584741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.