Evidence map›Paper›PMID 28243924›Full record

ArticleIntensive care medicine experimental2017

The respiratory pressure-abdominal volume curve in a porcine model.

Adrian Regli, Bart Leon De Keulenaer, Bhajan Singh, Lisen Emma Hockings, Bill Noffsinger, Peter Vernon van Heerden

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Review
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adrian RegliIntensive Care Unit, Fiona Stanley Hospital, 102-118 Murdoch Drive, Murdoch (Perth), WA, 6150, Australia. adrian.regli@gmail.com.ORCID http://orcid.org/0000-0002-3960-6013
Bart Leon De KeulenaerIntensive Care Unit, Fiona Stanley Hospital, 102-118 Murdoch Drive, Murdoch (Perth), WA, 6150, Australia.
Bhajan SinghDepartment of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands (Perth), WA, 6009, Australia.
Lisen Emma HockingsIntensive Care Unit, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands (Perth), WA, 6009, Australia.
Bill NoffsingerDepartment of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands (Perth), WA, 6009, Australia.
Peter Vernon van HeerdenIntensive Care Unit, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands (Perth), WA, 6009, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing intra-abdominal volume (IAV) can lead to intra-abdominal hypertension (IAH) or abdominal compartment syndrome. Both are associated with raised morbidity and mortality. IAH can increase airway pressures and impair ventilation. The relationship between increasing IAV and airway pressures is not known. We therefore assessed the effect of increasing IAV on airway and intra-abdominal pressures (IAP).

methodsSeven pigs (41.4 +/-8.5 kg) received standardized anesthesia and mechanical ventilation. A latex balloon inserted in the peritoneal cavity was inflated in 1-L increments until IAP exceeded 40 cmH

resultsAn exponential equation best described the measured pressure-volume curves. Raising IAV increased pP

conclusionsThe exponential nature of the effect of IAV on pP

Indexed as

Abdominal complianceAbdominal volumeAirway pressuresIntra-abdominal hypertensionIntra-abdominal pressureRespiratory compliance

Identifiers

PMID28243924
PMCPMC5328886

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.