ArticleBrain structure & function2017
Synaptic connections formed by patchy projections of pyramidal cells in the superficial layers of cat visual cortex.
Article in Brain structure & function, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- A brain-constrained neural model of cognition and language with NEST: transitioning from the Felix framework.Cognitive neurodynamics · 2026Article
- Modular Organization of Signal Transmission in Primate Somatosensory Cortex.Frontiers in neuroanatomy · 2022Article
- Clustered Intrinsic Connections: Not a Single System.Frontiers in systems neuroscience · 2022Article
- Cytochrome oxidase "blobs": a call for more anatomy.Brain structure & function · 2021Review
- Article
- Reduced Axon Calibre in the Associative Striatum of theBrain sciences · 2021Article
- Distinctive Spatial and Laminar Organization of Single Axons from Lateral Pulvinar in the Macaque.Vision (Basel, Switzerland) · 2019Review
- Translaminar circuits formed by the pyramidal cells in the superficial layers of cat visual cortex.Brain structure & function · 2018Article
- Axon Collaterals and Brain States.Frontiers in systems neuroscience · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The present study is the first to describe quantitatively the patterns of synaptic connections made by the patchy network of pyramidal cell axons in the superficial layers of cat V1 in relation to the orientation map. Intrinsic signal imaging of the orientation map was combined with 3D morphological reconstructions of physiologically-characterized neurons at light and electron microscope levels. A Similarity Index (SI) expressed the similarity of the orientation domain of a given bouton cluster to that of its parent dendritic tree. Six pyramidal cells whose axons had a wide range of SIs were examined. Boutons were sampled from five local and five distal clusters, and from the linear segments that link the clusters. The synaptic targets were reconstructed by serial section electron microscopy. Of the 233 synapses examined, 182 synapses were formed with spiny neurons, the remainder with smooth neurons. The proportion of smooth neurons that were synaptic targets varied greatly (from 0 to 50%) between the cluster samples, but was not correlated with the SI. The postsynaptic density sizes were similar for synapses in local and distal clusters, regardless of their SI. This heterogeneity in the synaptic targets of single cells within the superficial layers is a network feature well-suited for context-dependent processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.