Evidence map›Paper›PMID 28243739›Full record

ArticleHistochemistry and cell biology2017

Characterization of mast cell populations using different methods for their identification.

Dmitri Atiakshin, Vera Samoilova, Igor Buchwalow, Werner Boecker, Markus Tiemann

Abstract read
PubMed Publisher
In one paragraph

Article in Histochemistry and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. COVID-19 and Lung Mast Cells: The Kallikrein-Kinin Activation Pathway.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Mastocytosis and Mast Cell Activation Disorders: Clearing the Air.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Review
  12. Mast cells and collagen fibrillogenesis.Histochemistry and cell biology · 2020
    Article
  13. In focus in HCB.Histochemistry and cell biology · 2020
    Article
  14. Article
  15. Article
  16. Mast cell chymase: morphofunctional characteristics.Histochemistry and cell biology · 2019
    Review
  17. In focus in HCB.Histochemistry and cell biology · 2019
    Article
  18. Article
  19. Article
  20. Tryptase as a polyfunctional component of mast cells.Histochemistry and cell biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dmitri AtiakshinResearch Institute of Experimental Biology and Medicine, Burdenko Voronezh State Medical University, Voronezh, Russia.
Vera SamoilovaInstitute for Hematopathology, Fangdieckstreet 75a, 22547, Hamburg, Germany.
Igor BuchwalowInstitute for Hematopathology, Fangdieckstreet 75a, 22547, Hamburg, Germany. buchwalow@pathologie-hh.de.
Werner BoeckerInstitute for Hematopathology, Fangdieckstreet 75a, 22547, Hamburg, Germany.
Markus TiemannInstitute for Hematopathology, Fangdieckstreet 75a, 22547, Hamburg, Germany.
Institut für Hämatopathologie Hamburg · DEVoronezh State Medical Academy named after N.N. Burdenko · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells are ubiquitous throughout the human tissues and play an essential role in physiology and pathology. For evaluation of patients with pathological conditions, mast cells were primarily detected using metachromatic staining with toluidine blue. In the last decades, the staining arsenal of pathologists was enriched with enzyme histochemical and immunohistochemical methods, and it was established that depending on species and tissue localization mast cells are not similar both in appearance and function. The aim of this study was to characterize different mast cell populations using the up-to-date methods of their identification. We compared standard metachromatic method for mast cells with enzyme histochemical detection of chloroacetyl esterase and with immunohistochemical detection of tryptase and chymase in human and rodent tissues. Combination of these methods allowed us to assay quantitatively mast cell populations in different organs of humans and rodents. Furthermore, we assessed the appropriate implementation of each of these methods for mast cell identification in diagnostic labs.

Indexed as

AnimalsCell CountCell SeparationGerbillinaeHistocytochemistryHumansMast CellsMiceStaining and LabelingTolonium ChlorideTolonium ChlorideChloroacetyl esteraseChymaseIdentificationMast cell populationsMetachromasiaTryptase

Identifiers

PMID28243739
OpenAlexW2593726777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.