Evidence map›Paper›PMID 28243700›Full record

ReviewCellular and molecular life sciences : CMLS2017

Mechanisms of collective cell movement lacking a leading or free front edge in vivo.

Hiroyuki Uechi, Erina Kuranaga

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Randomly Distributed K14Cancer research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hiroyuki UechiLaboratory for Histogenetic Dynamics, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan.
Erina KuranagaLaboratory for Histogenetic Dynamics, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan. erina.kuranaga.d1@tohoku.ac.jp.ORCID 0000-0001-6300-2087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collective cell movement is one of the strategies for achieving the complex shapes of tissues and organs. In this process, multiple cells within a group held together by cell-cell adhesion acquire mobility and move together in the same direction. In some well-studied models of collective cell movement, the mobility depends strongly on traction generated at the leading edge by cells located at the front. However, recent advances in live-imaging techniques have led to the discovery of other types of collective cell movement lacking a leading edge or even a free edge at the front, in a diverse array of morphological events, including tubule elongation, epithelial sheet extension, and tissue rotation. We herein review some of the developmental events that are organized by collective cell movement and attempt to elucidate the underlying cellular and molecular mechanisms, which include membrane protrusions, guidance cues, cell intercalation, and planer cell polarity, or chirality pathways.

Indexed as

Cell MovementAnimalsCell AdhesionCell CommunicationCell PolarityEpithelial CellsHumansCell intercalationGuidance cueLeading edgeMembrane protrusionPlaner cell chiralityPlaner cell polarity

Identifiers

PMID28243700
PMCPMC11107506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.