Evidence map›Paper›PMID 28243506›Full record

ArticleIntravital2014

Optimization of the dorsal skinfold window chamber model and multi-parametric characterization of tumor-associated vasculature.

Azusa Maeda, Ralph S DaCosta

Abstract read
In one paragraph

Article in Intravital, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Epigenetic basis of diabetic vasculopathy.Frontiers in endocrinology · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Cellular imaging in rheumatic diseases.Nature reviews. Rheumatology · 2015
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Azusa MaedaOntario Cancer Institute; University Health Network; Toronto, ON Canada; Department of Medical Biophysics; University of Toronto; Toronto, ON Canada.
Ralph S DaCostaOntario Cancer Institute; University Health Network; Toronto, ON Canada; Department of Medical Biophysics; University of Toronto; Toronto, ON Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dorsal skinfold window chamber (DSWC) model is a unique tool that enables analysis of various aspects of tumor biology and therapeutic response. Although the protocol for the murine DSWC model is standardized, certain tumors fail to grow or require a particular environment to promote growth. Given such limitations, we optimized the DSWC model for a slow-growing tumor that regresses spontaneously in the standard protocol. We further characterized the vascular network in the tumor model compared with that of non-tumor-bearing mice and observed significant differences in multiple parameters related to vascular structure and function.

Indexed as

dorsal skinfold window chamber modelfluorescenceperfusiontortuosityvascular imagingvascularity

Identifiers

PMID28243506
PMCPMC5312716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.